Idiopathic remitting seronegative symmetrical synovitis with pitting edema syndrome associated with bilateral pleural and pericardial effusions: a case report

Remitting seronegative symmetrical synovitis with pitting edema syndrome is characterized by symmetrical synovitis with pitting edema in the dorsum of the hands or feet. Most cases of remitting seronegative symmetrical synovitis with pitting edema syndrome are idiopathic, but some are secondary to m...

Full description

Saved in:
Bibliographic Details
Published in:Journal of medical case reports 2016-07, Vol.10 (1), p.198-198, Article 198
Main Authors: Yanamoto, Shozaburo, Fukae, Jiro, Fukiyama, Yurie, Fujioka, Shinsuke, Ouma, Shinji, Tsuboi, Yoshio
Format: Article
Language:English
Subjects:
Adrenal Cortex Hormones - therapeutic use
Aged
Care and treatment
Case Report
Case studies
Complications and side effects
Development and progression
Diagnosis, Differential
Disease
Dropsy
Edema
Edema - complications
Edema - diagnosis
Edema - drug therapy
Female
Humans
Medical treatment
Pericardial effusion
Pericardial Effusion - complications
Pericardial Effusion - diagnosis
Pericardial Effusion - drug therapy
Pleural Effusion - complications
Pleural Effusion - diagnosis
Pleural Effusion - drug therapy
Syndrome
Synovitis - complications
Synovitis - diagnosis
Synovitis - drug therapy
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Remitting seronegative symmetrical synovitis with pitting edema syndrome is characterized by symmetrical synovitis with pitting edema in the dorsum of the hands or feet. Most cases of remitting seronegative symmetrical synovitis with pitting edema syndrome are idiopathic, but some are secondary to malignancy, autoimmune disease, or neurodegenerative disorders. Pleural and pericardial effusions are unusual complications in idiopathic remitting seronegative symmetrical synovitis with pitting edema syndrome. A 74-year-old Japanese woman presented to our hospital with arthralgia and pitting edema in her feet. She had pain in multiple joints, peripheral edema, and a markedly elevated erythrocyte sedimentation rate. Enhanced computed tomography and laboratory data showed no evidence of malignancy. These findings suggested that she had idiopathic remitting seronegative symmetrical synovitis with pitting edema syndrome. She also developed respiratory distress because of bilateral pleural and pericardial effusions. Laboratory data showed that serum vascular endothelial growth factor and interleukin-6 were significantly elevated. After administration of steroids, her pleural and pericardial effusions decreased and finally disappeared. Furthermore, vascular endothelial growth factor and interleukin-6 decreased when the pleural and pericardial effusions disappeared. Here we report the case of a patient with idiopathic remitting seronegative symmetrical synovitis with pitting edema syndrome associated with life-threatening complications, including bilateral pleural and pericardial effusions during the course of the illness, which led to respiratory failure and atrial fibrillation. Elevated vascular endothelial growth factor and interleukin-6 may be associated with the cause of pleural and pericardial effusions in idiopathic remitting seronegative symmetrical synovitis with pitting edema syndrome.
ISSN:1752-1947
1752-1947
DOI:10.1186/s13256-016-0983-7