Fabrication of naturel pumice/hydroxyapatite composite for biomedical engineering

We evaluated the Bovine hydroxyapatite (BHA) structure. BHA powder was admixed with 5 and 10 wt% natural pumice (NP). Compression strength, Vickers micro hardness, Fourier transform infrared spectroscopy, scanning electron microscopy (SEM) and X-ray diffraction studies were performed on the final NP...

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Published in:Biomedical engineering online 2016-07, Vol.15 (1), p.81-81, Article 81
Main Authors: Komur, Baran, Lohse, Tim, Can, Hatice Merve, Khalilova, Gulnar, Geçimli, Zeynep Nur, Aydoğdu, Mehmet Onur, Kalkandelen, Cevriye, Stan, George E, Sahin, Yesim Muge, Sengil, Ahmed Zeki, Suleymanoglu, Mediha, Kuruca, Serap Erdem, Oktar, Faik Nuzhet, Salman, Serdar, Ekren, Nazmi, Ficai, Anton, Gunduz, Oguzhan
Format: Article
Language:English
Subjects:
Animals
Biocompatible Materials - chemistry
Biomaterials
Biomedical Engineering
Cattle
Cell Line, Tumor
Durapatite - chemistry
Humans
Hydroxyapatites
Materials Testing
Mechanical Phenomena
Porosity
Production processes
Pumice
Silicates - chemistry
Temperature
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Summary:We evaluated the Bovine hydroxyapatite (BHA) structure. BHA powder was admixed with 5 and 10 wt% natural pumice (NP). Compression strength, Vickers micro hardness, Fourier transform infrared spectroscopy, scanning electron microscopy (SEM) and X-ray diffraction studies were performed on the final NP-BHA composite products. The cells proliferation was investigated by MTT assay and SEM. Furthermore, the antimicrobial activity of NP-BHA samples was interrogated. Variances in the sintering temperature (for 5 wt% NP composites) between 1000 and 1300 °C, reveal about 700 % increase in the microhardness (~100 and 775 HV, respectively). Composites prepared at 1300 °C demonstrate the greatest compression strength with comparable result for 5 wt% NP content (87 MPa), which are significantly better than those for 10 wt% and those that do not include any NP (below 60 MPa, respectively). The results suggested the optimal parameters for the preparation of NP-BHA composites with increased mechanical properties and biocompatibility. Changes in micro-hardness and compression strength can be tailored by the tuning the NP concentration and sintering temperature. NP-BHA composites have demonstrated a remarkable potential for biomedical engineering applications such as bone graft and implant.
ISSN:1475-925X
1475-925X
DOI:10.1186/s12938-016-0203-0