Robust dipstick urinalysis using a low-cost, micro-volume slipping manifold and mobile phone platform

We introduce a novel manifold and companion software for dipstick urinalysis that eliminate many of the aspects that are traditionally plagued by user error: precise sample delivery, accurate readout timing, and controlled lighting conditions. The proposed all-acrylic slipping manifold is reusable,...

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Bibliographic Details
Published in:Lab on a chip 2016-01, Vol.16 (11), p.2069-2078
Main Authors: Smith, Gennifer T, Dwork, Nicholas, Khan, Saara A, Millet, Matthew, Magar, Kiran, Javanmard, Mehdi, Ellerbee Bowden, Audrey K
Format: Article
Language:English
Subjects:
Cell phones
Computer programs
Illumination
Manifolds
Software
Strategy
Time measurements
Urinalysis
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Summary:We introduce a novel manifold and companion software for dipstick urinalysis that eliminate many of the aspects that are traditionally plagued by user error: precise sample delivery, accurate readout timing, and controlled lighting conditions. The proposed all-acrylic slipping manifold is reusable, reliable, and low in cost. A simple timing mechanism ensures results are read out at the appropriate time. Results are obtained by capturing videos using a mobile phone and by analyzing them using custom-designed software. We show that the results obtained with the proposed device are as accurate and consistent as a properly executed dip-and-wipe method, the industry gold-standard, suggesting the potential for this strategy to enable confident urinalysis testing in home environments.
ISSN:1473-0197
1473-0189
DOI:10.1039/c6lc00340k