PathwaysWeb: a gene pathways API with directional interactions, expanded gene ontology, and versioning

PathwaysWeb is a resource-based, well-documented web system that provides publicly available information on genes, biological pathways, Gene Ontology (GO) terms, gene-gene interaction networks (importantly, with the directionality of interactions) and links to key-related PubMed documents. The Pathw...

Full description

Saved in:
Bibliographic Details
Published in:Bioinformatics (Oxford, England) England), 2016-01, Vol.32 (2), p.312-314
Main Authors: Melott, James M, Weinstein, John N, Broom, Bradley M
Format: Article
Language:English
Subjects:
Algorithms
Animals
Applications Notes
Computational Biology - methods
Databases, Factual
Gene Ontology
Gene Regulatory Networks
Humans
Information Storage and Retrieval
Internet
Mice
Protein Interaction Maps
Signal Transduction
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:PathwaysWeb is a resource-based, well-documented web system that provides publicly available information on genes, biological pathways, Gene Ontology (GO) terms, gene-gene interaction networks (importantly, with the directionality of interactions) and links to key-related PubMed documents. The PathwaysWeb API simplifies the construction of applications that need to retrieve and interrelate information across multiple, pathway-related data types from a variety of original data sources. PathwaysBrowser is a companion website that enables users to explore the same integrated pathway data. The PathwaysWeb system facilitates reproducible analyses by providing access to all versions of the integrated datasets. Although its GO subsystem includes data for mouse, PathwaysWeb currently focuses on human data. However, pathways for mouse and many other species can be inferred with a high success rate from human pathways. PathwaysWeb can be accessed via the Internet at http://bioinformatics.mdanderson.org/main/PathwaysWeb:Overview. jmmelott@mdanderson.org Supplementary data are available at Bioinformatics online.
ISSN:1367-4803
1367-4811
DOI:10.1093/bioinformatics/btv554