HLA antigens in chronic inflammatory demyelinating polyneuropathy

HLA typing of 71 patients with chronic inflammatory demyelinating polyneuropathy (CIDP) showed an overall increase in frequencies of HLA-A3, -B7, -DR2 as well as concomitantly decreased frequencies of HLA-44 and DR7. The strongest associations were seen with HLA-DR2, -DR7 and -B44 in CIDP overall, a...

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Bibliographic Details
Published in:Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 1990-02, Vol.53 (2), p.170-172
Main Authors: Feeney, D J, Pollard, J D, McLeod, J G, Stewart, G J, Doran, T J
Format: Article
Language:English
Subjects:
Biological and medical sciences
Chronic Disease
Gene Frequency - genetics
HLA Antigens - genetics
HLA-A Antigens - genetics
HLA-B Antigens - genetics
HLA-DR Antigens - genetics
Humans
Medical sciences
Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis
Neurology
Phenotype
Polyradiculoneuropathy - genetics
Recurrence
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Summary:HLA typing of 71 patients with chronic inflammatory demyelinating polyneuropathy (CIDP) showed an overall increase in frequencies of HLA-A3, -B7, -DR2 as well as concomitantly decreased frequencies of HLA-44 and DR7. The strongest associations were seen with HLA-DR2, -DR7 and -B44 in CIDP overall, although they did not reach statistical significance.
ISSN:0022-3050
1468-330X
DOI:10.1136/jnnp.53.2.170