A promising concept of combination therapy for positional obstructive sleep apnea

Purpose The objective of this randomized controlled trial was to assess the additional effect of a chest-worn sleep position trainer (SPT) in patients with residual supine-dependent obstructive sleep apnea (sdOSA) under mandibular advancement device (MAD) therapy. Methods Baseline and follow-up poly...

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Bibliographic Details
Published in:Sleep & breathing 2015-05, Vol.19 (2), p.637-644
Main Authors: Dieltjens, Marijke, Vroegop, Anneclaire V., Verbruggen, Annelies E., Wouters, Kristien, Willemen, Marc, De Backer, Wilfried A., Verbraecken, Johan A., Van de Heyning, Paul H., Braem, Marc J., de Vries, Nico, Vanderveken, Olivier M.
Format: Article
Language:English
Subjects:
Adult
Combined Modality Therapy
Dentistry
Female
Follow-Up Studies
Humans
Internal Medicine
Male
Mandibular Advancement - instrumentation
Medical treatment
Medicine
Medicine & Public Health
Middle Aged
Neurology
Occlusal Splints
Original
Original Article
Otorhinolaryngology
Patient Positioning - instrumentation
Pediatrics
Physical Therapy Modalities - instrumentation
Pneumology/Respiratory System
Polysomnography
Respiration
Sleep apnea
Sleep Apnea, Obstructive - physiopathology
Sleep Apnea, Obstructive - therapy
Supine Position - physiology
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Summary:Purpose The objective of this randomized controlled trial was to assess the additional effect of a chest-worn sleep position trainer (SPT) in patients with residual supine-dependent obstructive sleep apnea (sdOSA) under mandibular advancement device (MAD) therapy. Methods Baseline and follow-up polysomnography with MAD were performed. Twenty patients with sdOSA under MAD therapy underwent two consecutive randomized polysomnographies: one with SPT and one with combination of SPT + MAD. Data are presented as median (quartile 1, quartile 3). Results The SPT reduced the time spent in supine sleeping position compared to baseline and MAD therapy. Both MAD and SPT were individually effective in reducing the overall apnea/hypopnea index (AHI) significantly when compared to baseline from 20.8 (15.1; 33.6)/h at baseline to 11.0 (6.7; 13.8)/h and to 11.1 (3.5; 17.7)/h with MAD or SPT, respectively. The combination of SPT + MAD further reduced the overall AHI to 5.7 (3.6; 7.4), which was significantly lower than with MAD alone ( p  
ISSN:1520-9512
1522-1709
DOI:10.1007/s11325-014-1068-8