Allergen immunotherapy for insect venom allergy: protocol for a systematic review

Background The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for the Management of Insect Venom Allergy. We seek to critically assess the effectiveness, cost‐effectiveness and safety of AIT in the man...

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Published in:	Clinical and translational allergy 2016-02, Vol.6 (1), p.6-n/a, Article 6
Main Authors:	Dhami, Sangeeta, Nurmatov, Ulugbek, Varga, Eva‐Maria, Sturm, Gunter, Muraro, Antonella, Akdis, Cezmi A., Antolín‐Amérigo, Darío, Bilò, M. Beatrice, Bokanovic, Danijela, Calderon, Moises A., Cichocka‐Jarosz, Ewa, Elberink, Joanna N. G. Oude, Gawlik, Radoslaw, Jakob, Thilo, Kosnik, Mitja, Lange, Joanna, Mingomataj, Ervin, Mitsias, Dimitris I., Mosbech, Holger, Pfaar, Oliver, Pitsios, Constantinos, Pravettoni, Valerio, Roberts, Graham, Ruëff, Franziska, Sin, Betül Ayşe, Sheikh, Aziz
Format:	Article
Language:	eng
Subjects:	Allergen immunotherapy Allergy Asthma Hymenoptera venom allergy Immunotherapy Insect sting Insect venom allergy Study Protocol Systemic sting reaction
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Summary:	Background The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for the Management of Insect Venom Allergy. We seek to critically assess the effectiveness, cost‐effectiveness and safety of AIT in the management of insect venom allergy. Methods We will undertake a systematic review, which will involve searching international biomedical databases for published, in progress and unpublished evidence. Studies will be independently screened against pre‐defined eligibility criteria and critically appraised using established instruments. Data will be descriptively and, if possible and appropriate, quantitatively synthesised. Discussion The findings from this review will be used to inform the development of recomendations for EAACI's Guidelines on AIT.
ISSN:	2045-7022 2045-7022