Ammi Visnaga in treatment of urolithiasis and hypertriglyceridemia

Ammi visnaga is a widely distributed Ancient Egyptian medicinal plant used for treatment of several diseases including urolithiasis (kidney stones). The active chemical constituents′ khellin and visnagin obtained from the A. visnaga seeds have activity of antilithiogenic and pleiotropic. However, li...

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Bibliographic Details
Published in:Pharmacognosy research 2015-10, Vol.7 (4), p.397-400
Main Authors: Bhagavathula, Akshaya, Mahmoud Al-Khatib, Ahed, Elnour, Asim, AlKalbani, Naama, Shehab, Abdulla
Format: Article
Language:English
Subjects:
Angina pectoris
Asthma
Baldness
Care and treatment
Cholesterol
Constipation
Crystallization
Diuretics
Enzymes
Hyperlipidemia
Hypertension
Kidney stones
Laboratories
Liver
Metabolism
Metabolites
Pain
Patients
Researchers
Short Communication
Smooth muscle
Stone
Studies
Triglycerides
Vitiligo
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Summary:Ammi visnaga is a widely distributed Ancient Egyptian medicinal plant used for treatment of several diseases including urolithiasis (kidney stones). The active chemical constituents′ khellin and visnagin obtained from the A. visnaga seeds have activity of antilithiogenic and pleiotropic. However, little is known about its activity on hypertriglyceridemia. The main aim of this review is to explore the use of A. visnaga in urolithiasis and to present a case of relevancy. We highlighted a case of a patient who has recurrent urethral stones and hypertriglyceridemia. The patient was treated with A. visnaga seeds, has recovered completely from ureteral stones and his high-density lipoprotein (HDL)-cholesterol low levels retained to normal after using of A. visnaga seeds for 10 days. The present case of A. visnaga seeds being local medicinal plant has shown the effect in treating urolithiasis with extended effect on raising HDL-cholesterol. These results may provide insights for in vitro studies for isolation of these biologically active compounds for potential in raising HDL-cholesterol. Whether or not the later effect can have clinical utility remains to be explored.
ISSN:0974-8490
0976-4836
0974-8490
DOI:10.4103/0974-8490.167894