Wernicke encephalopathy as rare complication of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

Highlights • Peritoneal carcinomatosis (PC) of gastric origin is a frequent event even in the early phase of the disease. • This is the first case, to our knowledge, of Wernicke Encephalopathy (WE) complicating CRS plus HIPEC used as treatment of peritoneal carcinomatosis of gastric origin. • WE is...

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Bibliographic Details
Published in:International journal of surgery case reports 2015-01, Vol.16, p.29-32
Main Authors: Macrì, Antonio, Fleres, Francesco, Ieni, Antonio, Rossitto, Maurizio, Mandolfino, Tommaso, Micalizzi, Salvatore, Iaropoli, Francesco, Mazzeo, Carmelo, Trovato, Massimo, Cucinotta, Eugenio, Saladino, Edoardo
Format: Article
Language:English
Subjects:
Case Report
Complications
Gastric cancer
HIPEC
Peritoneal carcinomatosis
Surgery
Wernicke Encephalopathy
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Summary:Highlights • Peritoneal carcinomatosis (PC) of gastric origin is a frequent event even in the early phase of the disease. • This is the first case, to our knowledge, of Wernicke Encephalopathy (WE) complicating CRS plus HIPEC used as treatment of peritoneal carcinomatosis of gastric origin. • WE is an uncommon neurological disorder characterized by a classical triad of symptoms: ataxia, ocular motor cranial neuropathies and changes in consciousness. • A deficiency of thiamine is responsible for the WE syndrome. • The application of Cytoreductive Surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) gives encouraging results. • A deficiency of thiamine is responsible for the WE syndrome.
ISSN:2210-2612
2210-2612
DOI:10.1016/j.ijscr.2015.09.012