Incidence of viral respiratory infections in a prospective cohort of outpatient and hospitalized children aged ≤5 years and its associated cost in Buenos Aires, Argentina

Although information about the incidence of viral respiratory illnesses and their associated cost can help health officials explore the value of interventions, data are limited from middle-income countries. During 2008-2010, we conducted a prospective cohort study and followed ~1,800 Argentinian chi...

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Bibliographic Details
Published in:BMC infectious diseases 2015-10, Vol.15 (1), p.447-447, Article 447
Main Authors: Marcone, Débora Natalia, Durand, Lizette O, Azziz-Baumgartner, Eduardo, Vidaurreta, Santiago, Ekstrom, Jorge, Carballal, Guadalupe, Echavarria, Marcela
Format: Article
Language:English
Subjects:
Argentina - epidemiology
Child, Hospitalized
Child, Preschool
Cohort Studies
Demography
Emergency Service, Hospital - economics
Female
Humans
Incidence
Infant
Male
Metapneumovirus - genetics
Metapneumovirus - isolation & purification
Microscopy, Fluorescence
Orthomyxoviridae - genetics
Orthomyxoviridae - isolation & purification
Outpatients
Paramyxoviridae Infections - epidemiology
Prospective Studies
Real-Time Polymerase Chain Reaction
Respiratory Syncytial Viruses - genetics
Respiratory Syncytial Viruses - isolation & purification
Respiratory Tract Infections - diagnosis
Respiratory Tract Infections - epidemiology
Respiratory Tract Infections - virology
Rhinovirus - genetics
Rhinovirus - isolation & purification
Virus Diseases - diagnosis
Virus Diseases - economics
Virus Diseases - epidemiology
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Summary:Although information about the incidence of viral respiratory illnesses and their associated cost can help health officials explore the value of interventions, data are limited from middle-income countries. During 2008-2010, we conducted a prospective cohort study and followed ~1,800 Argentinian children aged ≤5 years to identify those children who were hospitalized or who sought care at an emergency room with any acute respiratory infection sign or symptom (e.g., rhinorrhea, cough, wheezing, tachypnea, retractions, or cyanosis). Respiratory samples were obtained for respiratory syncytial virus, influenza, parainfluenza, adenovirus, and metapneumovirus testing by immunofluorescence and for rhinovirus by real-time reverse transcription polymerase chain reaction. The incidence of respiratory syncytial virus (24/1000 children-years), human metapneumovirus (8/1000 children-years), and influenza (8/1000 children-years) illnesses was highest among hospitalized children aged
ISSN:1471-2334
1471-2334
DOI:10.1186/s12879-015-1213-4