Diffusion-weighted imaging to differentiate metastatic from non-metastatic retropharyngeal lymph nodes in nasopharyngeal carcinoma

To evaluate the diagnostic value of diffusion-weighted MRI for differentiating metastatic from non-metastatic retropharyngeal lymph nodes (RLNs) in patients with nasopharyngeal carcinoma (NPC). Untreated patients with NPC (n = 145) were scanned with both morphological MRI and diffusion-weighted imag...

Full description

Saved in:
Bibliographic Details
Published in:Dento-maxillo-facial radiology 2015-03, Vol.44 (3), p.20140126-20140126
Main Authors: Li, H, Liu, X-W, Geng, Z-J, Wang, D-L, Xie, C-M
Format: Article
Language:English
Subjects:
Adult
Aged
China
Contrast Media
Dentistry
Diagnosis, Differential
Diffusion Magnetic Resonance Imaging
Female
Humans
Lymphatic Metastasis - pathology
Male
Middle Aged
Nasopharyngeal Neoplasms - diagnosis
Nasopharyngeal Neoplasms - pathology
Neck
Retrospective Studies
Sensitivity and Specificity
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To evaluate the diagnostic value of diffusion-weighted MRI for differentiating metastatic from non-metastatic retropharyngeal lymph nodes (RLNs) in patients with nasopharyngeal carcinoma (NPC). Untreated patients with NPC (n = 145) were scanned with both morphological MRI and diffusion-weighted imaging (DWI). RLNs (n = 335) were classified as metastatic on the basis of response to therapy as assessed on follow-up MRI. Morphological (short- and long-axial diameters) and functional [mean apparent diffusion coefficient (ADC) and minimum ADC values] parameters of the RLNs were derived from DWI and compared between metastatic and non-metastatic groups. A receiver operating characteristic curve and the area under the curve were used to evaluate the effectiveness of individual criteria and to generate threshold values to diagnose RLN metastases. Statistically significant differences between metastatic and non-metastatic RLNs were found for all four parameters derived from DWI (p 
ISSN:0250-832X
1476-542X
DOI:10.1259/dmfr.20140126