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What's Age Got to do with it? A Review of Contemporary Revascularization in the Elderly
Currently a quarter of all patients treated with percutanous coronary intervention (PCI) are aged >75 years, with this proportion steadily growing. This subset of patients have a number of unique characteristics, such as a greater number of cardiovascular risk factors and frequently a larger burd...
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| Published in: | Current cardiology reviews 2015-01, Vol.11 (3), p.199-208 |
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| Main Authors: | , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-b548t-845523065e89b44f6270793c5cd1a8dfeba02dc72b2b685908164877a2c0d7193 |
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| container_end_page | 208 |
| container_issue | 3 |
| container_start_page | 199 |
| container_title | Current cardiology reviews |
| container_volume | 11 |
| creator | Vandermolen, Sebastian Abbott, Jane De Silva, Kalpa |
| description | Currently a quarter of all patients treated with percutanous coronary intervention (PCI) are
aged >75 years, with this proportion steadily growing. This subset of patients have a number of unique
characteristics, such as a greater number of cardiovascular risk factors and frequently a larger burden
of coronary artery disease, when compared to younger patients, therefore potentially deriving increased
benefit from revascularization. Nonetheless this population are also more likely to experience
procedural complications, secondary to age-related physiological alterations, increased frailty and increased
prevalence of other co-morbidities. This article reviews the various aspects and data available
to clinicians pertaining to and guiding revascularization in the elderly, including the use of adjuvant pharmacotherapy,
specific considerations when considering age-related physiology, and revascularization in acute coronary syndromes. |
| doi_str_mv | 10.2174/1573403X10666141020110122 |
| format | article |
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aged >75 years, with this proportion steadily growing. This subset of patients have a number of unique
characteristics, such as a greater number of cardiovascular risk factors and frequently a larger burden
of coronary artery disease, when compared to younger patients, therefore potentially deriving increased
benefit from revascularization. Nonetheless this population are also more likely to experience
procedural complications, secondary to age-related physiological alterations, increased frailty and increased
prevalence of other co-morbidities. This article reviews the various aspects and data available
to clinicians pertaining to and guiding revascularization in the elderly, including the use of adjuvant pharmacotherapy,
specific considerations when considering age-related physiology, and revascularization in acute coronary syndromes.</description><identifier>ISSN: 1573-403X</identifier><identifier>EISSN: 1875-6557</identifier><identifier>DOI: 10.2174/1573403X10666141020110122</identifier><identifier>PMID: 25329923</identifier><language>eng</language><publisher>United Arab Emirates: Bentham Science Publishers Ltd</publisher><subject>Aged ; Cardiovascular Diseases - epidemiology ; Cardiovascular Diseases - therapy ; Comorbidity ; Humans ; Myocardial Revascularization ; Percutaneous Coronary Intervention ; Risk Factors</subject><ispartof>Current cardiology reviews, 2015-01, Vol.11 (3), p.199-208</ispartof><rights>2015 Bentham Science Publishers 2015 Kalpa De Silva</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b548t-845523065e89b44f6270793c5cd1a8dfeba02dc72b2b685908164877a2c0d7193</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558351/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558351/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,733,786,790,891,27957,27958,53827,53829</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25329923$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vandermolen, Sebastian</creatorcontrib><creatorcontrib>Abbott, Jane</creatorcontrib><creatorcontrib>De Silva, Kalpa</creatorcontrib><title>What's Age Got to do with it? A Review of Contemporary Revascularization in the Elderly</title><title>Current cardiology reviews</title><addtitle>CCR</addtitle><description>Currently a quarter of all patients treated with percutanous coronary intervention (PCI) are
aged >75 years, with this proportion steadily growing. This subset of patients have a number of unique
characteristics, such as a greater number of cardiovascular risk factors and frequently a larger burden
of coronary artery disease, when compared to younger patients, therefore potentially deriving increased
benefit from revascularization. Nonetheless this population are also more likely to experience
procedural complications, secondary to age-related physiological alterations, increased frailty and increased
prevalence of other co-morbidities. This article reviews the various aspects and data available
to clinicians pertaining to and guiding revascularization in the elderly, including the use of adjuvant pharmacotherapy,
specific considerations when considering age-related physiology, and revascularization in acute coronary syndromes.</description><subject>Aged</subject><subject>Cardiovascular Diseases - epidemiology</subject><subject>Cardiovascular Diseases - therapy</subject><subject>Comorbidity</subject><subject>Humans</subject><subject>Myocardial Revascularization</subject><subject>Percutaneous Coronary Intervention</subject><subject>Risk Factors</subject><issn>1573-403X</issn><issn>1875-6557</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNp1kUFv1DAQhSMEomXhLyBzgsuC7cRJfAGtVqUgVUJCoHIbOc7sxuDYwXZ2Vc78cBy2VHDg5NHMN2-e_IriGaMvOWuqV0w0ZUXLL4zWdc0qRjlljDLO7xXnrG3EuhaiuZ_rzK0X8Kx4FONXSgWvJXtYnHFRcil5eV5cXw8qPY9ks0dy6RNJnvSeHE0aiElvyIZ8xIPBI_E7svUu4Tj5oMLN0lZRz1YF80Ml4x0xjqQByYXtMdibx8WDnbIRn9y-q-Lz24tP23frqw-X77ebq3Unqjat20oIXtJaYCu7qtrVvKGNLLXQPVNtv8NOUd7rhne8q1shacvqqm0axTXtGybLVfH6pDvN3Yi9RpeCsjAFM2ab4JWBfyfODLD3B8iH21KwLPDiViD47zPGBKOJGq1VDv0cgdUtk1Qu_70q5AnVwccYcHd3hlFYgoH_BpN3n_7t827zTxIZ-HkCumx0UGPUBp3GO3BIaYLj8Qg4B_ymIlrUCbQfwU_o5mBznfNxCaZhgj26gKBCMtoimBjdb2-wmIODt_OIwNgymBFKiJPa54aU5S-CRLvf</recordid><startdate>20150101</startdate><enddate>20150101</enddate><creator>Vandermolen, Sebastian</creator><creator>Abbott, Jane</creator><creator>De Silva, Kalpa</creator><general>Bentham Science Publishers Ltd</general><general>Bentham Science Publishers</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20150101</creationdate><title>What's Age Got to do with it? A Review of Contemporary Revascularization in the Elderly</title><author>Vandermolen, Sebastian ; Abbott, Jane ; De Silva, Kalpa</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b548t-845523065e89b44f6270793c5cd1a8dfeba02dc72b2b685908164877a2c0d7193</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Aged</topic><topic>Cardiovascular Diseases - epidemiology</topic><topic>Cardiovascular Diseases - therapy</topic><topic>Comorbidity</topic><topic>Humans</topic><topic>Myocardial Revascularization</topic><topic>Percutaneous Coronary Intervention</topic><topic>Risk Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vandermolen, Sebastian</creatorcontrib><creatorcontrib>Abbott, Jane</creatorcontrib><creatorcontrib>De Silva, Kalpa</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Current cardiology reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vandermolen, Sebastian</au><au>Abbott, Jane</au><au>De Silva, Kalpa</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>What's Age Got to do with it? A Review of Contemporary Revascularization in the Elderly</atitle><jtitle>Current cardiology reviews</jtitle><addtitle>CCR</addtitle><date>2015-01-01</date><risdate>2015</risdate><volume>11</volume><issue>3</issue><spage>199</spage><epage>208</epage><pages>199-208</pages><issn>1573-403X</issn><eissn>1875-6557</eissn><notes>ObjectType-Article-2</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-3</notes><notes>content type line 23</notes><notes>ObjectType-Review-1</notes><abstract>Currently a quarter of all patients treated with percutanous coronary intervention (PCI) are
aged >75 years, with this proportion steadily growing. This subset of patients have a number of unique
characteristics, such as a greater number of cardiovascular risk factors and frequently a larger burden
of coronary artery disease, when compared to younger patients, therefore potentially deriving increased
benefit from revascularization. Nonetheless this population are also more likely to experience
procedural complications, secondary to age-related physiological alterations, increased frailty and increased
prevalence of other co-morbidities. This article reviews the various aspects and data available
to clinicians pertaining to and guiding revascularization in the elderly, including the use of adjuvant pharmacotherapy,
specific considerations when considering age-related physiology, and revascularization in acute coronary syndromes.</abstract><cop>United Arab Emirates</cop><pub>Bentham Science Publishers Ltd</pub><pmid>25329923</pmid><doi>10.2174/1573403X10666141020110122</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1573-403X |
| ispartof | Current cardiology reviews, 2015-01, Vol.11 (3), p.199-208 |
| issn | 1573-403X 1875-6557 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4558351 |
| source | PubMed Central |
| subjects | Aged Cardiovascular Diseases - epidemiology Cardiovascular Diseases - therapy Comorbidity Humans Myocardial Revascularization Percutaneous Coronary Intervention Risk Factors |
| title | What's Age Got to do with it? A Review of Contemporary Revascularization in the Elderly |
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