What's Age Got to do with it? A Review of Contemporary Revascularization in the Elderly

Currently a quarter of all patients treated with percutanous coronary intervention (PCI) are aged >75 years, with this proportion steadily growing. This subset of patients have a number of unique characteristics, such as a greater number of cardiovascular risk factors and frequently a larger burd...

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Bibliographic Details
Published in:Current cardiology reviews 2015-01, Vol.11 (3), p.199-208
Main Authors: Vandermolen, Sebastian, Abbott, Jane, De Silva, Kalpa
Format: Article
Language:English
Subjects:
Aged
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - therapy
Comorbidity
Humans
Myocardial Revascularization
Percutaneous Coronary Intervention
Risk Factors
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Summary:Currently a quarter of all patients treated with percutanous coronary intervention (PCI) are aged >75 years, with this proportion steadily growing. This subset of patients have a number of unique characteristics, such as a greater number of cardiovascular risk factors and frequently a larger burden of coronary artery disease, when compared to younger patients, therefore potentially deriving increased benefit from revascularization. Nonetheless this population are also more likely to experience procedural complications, secondary to age-related physiological alterations, increased frailty and increased prevalence of other co-morbidities. This article reviews the various aspects and data available to clinicians pertaining to and guiding revascularization in the elderly, including the use of adjuvant pharmacotherapy, specific considerations when considering age-related physiology, and revascularization in acute coronary syndromes.
ISSN:1573-403X
1875-6557
DOI:10.2174/1573403X10666141020110122