Autism Symptomatology in Boys with Fragile X Syndrome: A Cross Sectional Developmental Trajectories Comparison with Nonsyndromic Autism Spectrum Disorder

Although males with fragile X syndrome (FXS) are frequently described as demonstrating autism symptomatology, there is much debate regarding whether the behavioral symptoms representing the core domains of autism are the result of the same or different underlying neurological/psychological mechanism...

Full description

Saved in:

Bibliographic Details
Published in:	Journal of autism and developmental disorders 2015-09, Vol.45 (9), p.2816-2832
Main Authors:	Thurman, Angela John, McDuffie, Andrea, Kover, Sara T., Hagerman, Randi J., Abbeduto, Leonard
Format:	Article
Language:	eng
Subjects:	Adolescent Age Differences Autism Autistic Disorder - complications Autistic Disorder - diagnosis Behavior Problems Behavioral Science and Psychology Child and School Psychology Comparative Analysis Expressive Language Fragile X Syndrome - complications Genetic Disorders Humans Language Development Male Males Neurosciences Nonverbal Ability Original Paper Pediatrics Pervasive Developmental Disorders Psychology Public Health Symptoms (Individual Disorders)
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Although males with fragile X syndrome (FXS) are frequently described as demonstrating autism symptomatology, there is much debate regarding whether the behavioral symptoms representing the core domains of autism are the result of the same or different underlying neurological/psychological mechanisms. The present study used a cross-sectional developmental trajectories approach to compare the profiles of autism symptomatology relative to chronological age (CA), nonverbal IQ, and expressive vocabulary ability between individuals with FXS and individuals with nonsyndromic ASD. Results suggest that the onset of autism symptoms and their developmental trajectories in males with FXS differ in important ways as a function of CA, nonverbal cognitive ability, and expressive vocabulary relative to males with nonsyndromic ASD. Theoretical and clinical implications are discussed.
ISSN:	0162-3257 1573-3432