Comparison of the gut microbiota composition between obese and non-obese individuals in a Japanese population, as analyzed by terminal restriction fragment length polymorphism and next-generation sequencing

Obesity has become one of the most serious social problems in developed countries, including Japan. The relationship between the gut microbiota and obesity has recently attracted the attention of many researchers. Although the gut microbiota was long thought to contribute to obesity, the exact assoc...

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Bibliographic Details
Published in:BMC gastroenterology 2015-08, Vol.15 (1), p.100-100, Article 100
Main Authors: Kasai, Chika, Sugimoto, Kazushi, Moritani, Isao, Tanaka, Junichiro, Oya, Yumi, Inoue, Hidekazu, Tameda, Masahiko, Shiraki, Katsuya, Ito, Masaaki, Takei, Yoshiyuki, Takase, Kojiro
Format: Article
Language:English
Subjects:
Adult
Asian People
Bacteroidetes - genetics
Bacteroidetes - isolation & purification
Body Mass Index
Care and treatment
Colonoscopy
Comparative analysis
DNA, Bacterial - analysis
Feces - microbiology
Female
Firmicutes - genetics
Firmicutes - isolation & purification
Gastroenterology
Gastrointestinal Microbiome - genetics
Gastrointestinal Tract - microbiology
Genetic aspects
Genetic polymorphisms
Humans
Japan
Male
Microbiota (Symbiotic organisms)
Middle Aged
Obesity
Obesity - microbiology
Patient outcomes
Polymorphism, Restriction Fragment Length
Sequence Analysis, DNA - methods
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Summary:Obesity has become one of the most serious social problems in developed countries, including Japan. The relationship between the gut microbiota and obesity has recently attracted the attention of many researchers. Although the gut microbiota was long thought to contribute to obesity, the exact association remains largely unknown. We examined the human gut microbiota composition in a Japanese population in order to determine its relationship to obesity. Stool samples from 23 non-obese subjects (body mass index [BMI]
ISSN:1471-230X
1471-230X
DOI:10.1186/s12876-015-0330-2