Clinical evolution of beta cell function in youth with diabetes: the SEARCH for Diabetes in Youth study

Aims/hypothesis Few studies have explored the epidemiology of beta cell loss in youth with diabetes. This report describes the evolution and major determinants of beta cell function, assessed by fasting C-peptide (FCP), in the SEARCH for Diabetes in Youth study. Methods Participants were 1,277 youth...

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Published in:Diabetologia 2012-12, Vol.55 (12), p.3359-3368
Main Authors: Dabelea, D., Mayer-Davis, E. J., Andrews, J. S., Dolan, L. M., Pihoker, C., Hamman, R. F., Greenbaum, C., Marcovina, S., Fujimoto, W., Linder, B., Imperatore, G., D’Agostino, R.
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Language:eng
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Summary:Aims/hypothesis Few studies have explored the epidemiology of beta cell loss in youth with diabetes. This report describes the evolution and major determinants of beta cell function, assessed by fasting C-peptide (FCP), in the SEARCH for Diabetes in Youth study. Methods Participants were 1,277 youth with diabetes (948 positive for diabetes autoantibodies [DAs] and 329 negative for DAs), diagnosed when aged
ISSN:0012-186X
1432-0428