Prognosis of critically ill cirrhotic versus non-cirrhotic patients: a comprehensive score-matched study

Cirrhotic patients admitted to an intensive care unit (ICU) have high mortality rates. The present study compared the characteristics and outcomes of critically ill patients admitted to the ICU with and without cirrhosis using the matched Acute Physiology and Chronic Health Evaluation III (APACHE II...

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Published in:BMC anesthesiology 2014-12, Vol.14 (1), p.123-123, Article 123
Main Authors: Fu, Chung-Ming, Chang, Chih-Hsiang, Fan, Pei-Chun, Tsai, Ming-Hung, Lin, Shu-Min, Kao, Kuo-Chin, Tian, Ya-Chung, Hung, Cheng-Chieh, Fang, Ji-Tseng, Yang, Chih-Wei, Chen, Yung-Chang
Format: Article
Language:English
Subjects:
Aged
APACHE
Case-Control Studies
Critical Illness - mortality
Female
Hospital Mortality
Hospitals
Humans
Intensive care
Intensive Care Units
Liver cirrhosis
Liver Cirrhosis - mortality
Liver Cirrhosis - physiopathology
Male
Middle Aged
Mortality
Organ Dysfunction Scores
Prognosis
Respiratory distress syndrome
Retrospective Studies
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Summary:Cirrhotic patients admitted to an intensive care unit (ICU) have high mortality rates. The present study compared the characteristics and outcomes of critically ill patients admitted to the ICU with and without cirrhosis using the matched Acute Physiology and Chronic Health Evaluation III (APACHE III) and Sequential Organ Failure Assessment (SOFA) scores. A retrospective case-control study was performed at the medical ICU of a tertiary-care hospital between January 2006 and December 2009. Patients were admitted with life-threatening complications and were matched for APACHE III and SOFA scores. Of 336 patients enrolled in the study, 87 in the cirrhosis or noncirrhosis group were matched according to the APACHE III scores. Another 55 patients with cirrhosis were matched to the 55 patients without cirrhosis according to the SOFA scores. Demographic data, aetiology of ICU admission, and laboratory variables were also evaluated. The overall hospital mortality rate in the patients with cirrhosis in the APACHE III-matched group was more than that in their counterparts (73.6% vs 57.5%, P = .026) but the rate did not differ significantly in the SOFA-matched group (61.8% vs 67.3%). In the APACHE III-matched group, the SOFA scores of patients with cirrhosis were significantly higher than those of patients without cirrhosis (P
ISSN:1471-2253
1471-2253
DOI:10.1186/1471-2253-14-123