Acupuncture/electroacupuncture enhances anti- depressant effect of Seroxat： the Symptom Checklist-90 scores

One hundred and five patients with primary unipolar depression were randomly divided into three groups： drug group （Seroxat administration）, acupuncture group （Seroxat plus acupunc- ture）, and electroacupuncture group （Seroxat plus acupuncture plus electroacupuncture）. Patients＇ symptoms were evalua...

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Bibliographic Details
Published in:Neural regeneration research 2014-01, Vol.9 (2), p.213-222
Main Authors: Chen, Junqi, Lin, Weirong, Wang, Shengxu, Wang, Chongqi, Li, Ganlong, Qu, Shanshan, Huang, Yong, Zhang, Zhangjin, Xiao, Wei
Format: Article
Language:English
Subjects:
Acupuncture
Antidepressants
Anxiety
Clinical Practice
Complications and side effects
Depression, Mental
Dosage and administration
Drug therapy
Hostility
Mental depression
Patient outcomes
Variance analysis
原发性
因子得分
抑郁症
治疗效果
电针
症状自评量表
针灸治疗
问卷调查
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Summary:One hundred and five patients with primary unipolar depression were randomly divided into three groups： drug group （Seroxat administration）, acupuncture group （Seroxat plus acupunc- ture）, and electroacupuncture group （Seroxat plus acupuncture plus electroacupuncture）. Patients＇ symptoms were evaluated using a psychometric questionnaire, the Symptom Check- list-90, before intervention and after 2, 4, 6 and 10 weeks of treatment. The individual factor scores and the total score from the Symptom Checldist-90 reduced in all three groups as treat- ment progressed. In the acupuncture and electroacupuncture groups, the total score and the factor scores for obsessive-compulsive symptoms, depression, and anxiety were significantly lower than those in the drug group. There was no significant difference in the factor scores or total scores between the acupuncture and electroacupuncture groups. Some factor scores in the electroacupuncture group, such as somatization, depression, hostility, and phobic anxiety, were increased at 10 weeks compared with the respective score immediately after the course of electroacupuncture at 6 weeks. Our findings indicate that administration of Seroxat alone or in combination with acupuncture/electroacupuncture can produce a significant effect in patients with primary unipolar depression. Furthermore, acupuncture/electroacupuncture has a rapid onset of therapeutic effect and produces a noticeable improvement in obsessive-compulsive, de- pressive and anxiety symptoms.
ISSN:1673-5374
1876-7958
DOI:10.4103/1673-5374.125353