Establishing protocols for tick containment at Biosafety Level 4

Abstract Tick borne diseases continue to emerge and have a great impact on public health and agriculture. In addition, many of the agents of tick borne diseases, which are classified as Biosafety Level 4 (BSL 4) viruses, have the potential to be used as biothreat agents. In spite of the known import...

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Bibliographic Details
Published in:	Pathogens and disease 2014-07, Vol.71 (2), p.282-285
Main Authors:	Thangamani, Saravanan, Bente, Dennis
Format:	Article
Language:	eng
Subjects:	Animals Arachnids Biomedical Research - methods biosafety Biosafety Level 4 Containment of Biohazards Disease Models, Animal Humans Ixodidae Lyme disease Occupational Health Parasitic diseases Prevention Tick-Borne Diseases - transmission Tick-Borne Diseases - virology ticks Ticks - physiology Ticks - virology
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Summary:	Abstract Tick borne diseases continue to emerge and have a great impact on public health and agriculture. In addition, many of the agents of tick borne diseases, which are classified as Biosafety Level 4 (BSL 4) viruses, have the potential to be used as biothreat agents. In spite of the known importance of these pathogens, there is an acute shortage of facilities and trained personnel to study the pathogenesis of tick borne diseases and to assess vaccine as well as other therapeutic interventions against tick borne diseases as they are transmitted in nature. We, at the Galveston National Laboratory, have developed facilities and protocols to safely work with BSL4 virus infected ticks. This capability adds tremendous value to the Nation’s training and research endeavors. In this report we describe the procedures and protocols to establish tick work in a BSL4 laboratory. In this report we describe the procedures and protocols to establish tick work in BSL4 laboratory. Figure Graphical Abstract Figure. In this report we describe the procedures and protocols to establish tick work in BSL4 laboratory.
ISSN:	2049-632X 2049-632X