Six-month survival and quality of life of intensive care patients with acute kidney injury

Acute kidney injury (AKI) has high incidence among the critically ill and associates with dismal outcome. Not only the long-term survival, but also the quality of life (QOL) of patients with AKI is relevant due to substantial burden of care regarding these patients. We aimed to study the long-term o...

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Bibliographic Details
Published in:Critical care (London, England) England), 2013-10, Vol.17 (5), p.R250-R250
Main Authors: Nisula, Sara, Vaara, Suvi T, Kaukonen, Kirsi-Maija, Reinikainen, Matti, Koivisto, Simo-Pekka, Inkinen, Outi, Poukkanen, Meri, Tiainen, Pekka, Pettilä, Ville, Korhonen, Anna-Maija
Format: Article
Language:English
Subjects:
Acute Kidney Injury - epidemiology
Acute Kidney Injury - therapy
Acute renal failure
Aged
Biomarkers - analysis
Critical Care
Female
Finland - epidemiology
Follow-Up Studies
Health aspects
Hospital patients
Humans
Incidence
Intensive care units
Kidney diseases
Length of Stay - statistics & numerical data
Male
Medical research
Medicine, Experimental
Middle Aged
Patient outcomes
Prospective Studies
Quality of Life
Surveys and Questionnaires
Survival Rate
Treatment Outcome
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Summary:Acute kidney injury (AKI) has high incidence among the critically ill and associates with dismal outcome. Not only the long-term survival, but also the quality of life (QOL) of patients with AKI is relevant due to substantial burden of care regarding these patients. We aimed to study the long-term outcome and QOL of patients with AKI treated in intensive care units. We conducted a predefined six-month follow-up of adult intensive care unit (ICU) patients from the prospective, observational, multi-centre FINNAKI study. We evaluated the QOL of survivors with the EuroQol (EQ-5D) questionnaire. We included all participating sites with at least 70% rate of QOL measurements in the analysis. Of the 1,568 study patients, 635 (40.5%, 95% confidence interval (CI) 38.0-43.0%) had AKI according to the Kidney Disease Improving Global Outcomes (KDIGO) criteria. Of the 635 AKI patients, 224 (35.3%), as compared to 154/933 (16.5%) patients without AKI, died within six months. Of the 1,190 survivors, 959 (80.6%) answered the EQ-5D questionnaire at six months. The QOL (median with Interquartile range, IQR) measured with the EQ-5D index and compared to age- and sex-matched general population was: 0.676 (0.520-1.00) versus 0.826 (0.812-0.859) for AKI patients, and 0.690 (0.533-1.00) versus 0.845 (0.812-0.882) for patients without AKI (P 
ISSN:1364-8535
1466-609X
DOI:10.1186/cc13076