Solitary fibrous tumors in abdomen and pelvis:Imaging characteristics and radiologic-pathologic correlation

AIM:To describe the imaging features of solitary fibrous tumors(SFTs)in the abdomen and pelvis,and the clinical and pathologic correlations.METHODS:Fifteen patients with pathologically confirmed SFTs in the abdomen and pelvis were retrospectively studied with imaging techniques by two radiologists i...

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Published in:World journal of gastroenterology : WJG 2014-05, Vol.20 (17), p.5066-5073
Main Authors: Li, Xue-Ming, Reng, Jing, Zhou, Peng, Cao, Ying, Cheng, Zhu-Zhong, Xiao, Yan, Xu, Guo-Hui
Format: Article
Language:English
Subjects:
Abdominal
Abdominal Neoplasms - chemistry
Abdominal Neoplasms - diagnosis
Abdominal Neoplasms - diagnostic imaging
Abdominal Neoplasms - pathology
Adult
Aged
Biomarkers, Tumor - analysis
Biopsy
Brief
Computed
Female
fibrous
Humans
imaging
Immunohistochemistry
Infant
Magnetic Resonance Imaging
Male
Middle Aged
Multimodal Imaging
Pelvic Neoplasms - chemistry
Pelvic Neoplasms - diagnosis
Pelvic Neoplasms - diagnostic imaging
Pelvic Neoplasms - pathology
Predictive Value of Tests
Retrospective Studies
Solitary
Solitary Fibrous Tumors - chemistry
Solitary Fibrous Tumors - diagnosis
Solitary Fibrous Tumors - diagnostic imaging
Solitary Fibrous Tumors - pathology
Tomography, X-Ray Computed
Tumor Burden
tumors
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Summary:AIM:To describe the imaging features of solitary fibrous tumors(SFTs)in the abdomen and pelvis,and the clinical and pathologic correlations.METHODS:Fifteen patients with pathologically confirmed SFTs in the abdomen and pelvis were retrospectively studied with imaging techniques by two radiologists in consensus.Patients underwent unenhanced and contrast-enhanced imaging,as follows:3 with computed tomography(CT)and magnetic resonance imaging(MRI)examination,8 with CT examination only,and 4 with MRI examination only.Image characteristics such as size,shape,margin,attenuation or intensity,and pattern of enhancement were analyzed and correlated with the microscopic findings identified from surgical specimens.In addition,patient demographics,presentation,and outcomes were recorded.RESULTS:Of the 15 patients evaluated,local symptoms related to the mass were found in 11 cases at admission.The size of the mass ranged from 3.4 to 25.1cm(mean,11.5 cm).Nine cases were round or oval,6were lobulated,and 10 displaced adjacent organs.Unenhanced CT revealed a heterogeneous isodense mass in 7 cases,homogeneous isodense mass in 3 cases,and punctuated calcification in one case.On MRI,most of the lesions(6/7)were heterogeneous isointense and heterogeneous hyperintense on T1-weighted images and T2-weighted images,respectively.All tumors showed moderate to marked enhancement.Heterogeneous enhancement was revealed in 11 lesions,and 7of these had cysts,necrosis,or hemorrhage.Early nonuniform enhancement with a radial area that proved to be a fibrous component was observed in 4 lesions,which showed progressive enhancement in the venous and delayed phase.No statistical difference in the imaging findings was observed between the histologically benign and malignant lesions.Three patients had local recurrence or metastasis at follow-up.CONCLUSION:Abdominal and pelvic SFTs commonly appeared as large,solid,well-defined,hypervascular masses with variable degrees of necrosis or cystic change that often displaced adjacent structures.
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v20.i17.5066