One-year mortality and predictors of death among hospital survivors of acute respiratory distress syndrome

Purpose Advances in supportive care and ventilator management for acute respiratory distress syndrome (ARDS) have resulted in declines in short-term mortality, but risks of death after survival to hospital discharge have not been well described. Our objective was to quantify the difference between s...

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Bibliographic Details
Published in:Intensive care medicine 2014-03, Vol.40 (3), p.388-396
Main Authors: Wang, Chen Yu, Calfee, Carolyn S., Paul, Devon W., Janz, David R., May, Addison K., Zhuo, Hanjing, Bernard, Gordon R., Matthay, Michael A., Ware, Lorraine B., Kangelaris, Kirsten Neudoerffer
Format: Article
Language:English
Subjects:
Adult
Aged
Anesthesiology
Cause of Death
Cohort analysis
Comorbidity
Creatine - blood
Critical care
Critical Care Medicine
Emergency Medicine
Female
Hospital Mortality
Hospitals
Humans
Illnesses
Intensive
Intensive care
Intensive Care Units - statistics & numerical data
Length of Stay - statistics & numerical data
Male
Medicine
Medicine & Public Health
Middle Aged
Mortality
Original
Outcome Assessment (Health Care)
Pain Medicine
Patient Discharge - statistics & numerical data
Pediatrics
Pneumology/Respiratory System
Prospective Studies
Respiratory distress syndrome
Respiratory Distress Syndrome, Adult - mortality
Risk Factors
Survivors
Time Factors
Ventilators
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Summary:Purpose Advances in supportive care and ventilator management for acute respiratory distress syndrome (ARDS) have resulted in declines in short-term mortality, but risks of death after survival to hospital discharge have not been well described. Our objective was to quantify the difference between short-term and long-term mortality in ARDS and to identify risk factors for death and causes of death at 1 year among hospital survivors. Methods This multi-intensive care unit, prospective cohort included patients with ARDS enrolled between January 2006 and February 2010. We determined the clinical characteristics associated with in-hospital and 1-year mortality among hospital survivors and utilized death certificate data to identify causes of death. Results Of 646 patients hospitalized with ARDS, mortality at 1 year was substantially higher (41 %, 95 % CI 37–45 %) than in-hospital mortality (24 %, 95 % CI 21–27 %), P  
ISSN:0342-4642
1432-1238
DOI:10.1007/s00134-013-3186-3