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An association between Helicobacter pylori and upper respiratory tract disease: Fact or fiction?

Helicobacter pylori(H. pylori) is a major cause of chronic gastritis and gastric ulcers and considerable evidence supports the notion that infection with this bacterium is also associated with gastric malignancy in addition to various other conditions including pulmonary, vascular and autoimmune dis...

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Bibliographic Details
Published in:World journal of gastroenterology : WJG 2014-02, Vol.20 (6), p.1470-1484
Main Authors: Kariya, Shin, Okano, Mitsuhiro, Nishizaki, Kazunori
Format: Article
Language:English
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Summary:Helicobacter pylori(H. pylori) is a major cause of chronic gastritis and gastric ulcers and considerable evidence supports the notion that infection with this bacterium is also associated with gastric malignancy in addition to various other conditions including pulmonary, vascular and autoimmune disorders. Gastric juice infected with H. pylori might play an important role in upper respiratory tract infection. Although direct and/or indirect mechanisms might be involved in the association between H. pylori and upper respiratory tract diseases, the etiological role of H. pylori in upper respiratory tract disorders has not yet been fully elucidated. Although various studies over the past two decades have suggested a relationship between H. pylori and upper respiratory tract diseases, the findings are inconsistent. The present overview describes the outcomes of recent investigations into the impact of H. pylori on upper respiratory tract and adjacent lesions.
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v20.i6.1470