Infectious diarrhoea in antiretroviral therapy-naïve HIV/AIDS patients in Kenya

Diarrhoea is a significant cause of morbidity and mortality in immunocompromised patients. The objectives of this study were to investigate the aetiological agents, risk factors and clinical features associated with diarrhoea in HIV/AIDS patients in Kenya. Sociodemographic, epidemiological and clini...

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Bibliographic Details
Published in:Transactions of the Royal Society of Tropical Medicine and Hygiene 2013-10, Vol.107 (10), p.631-638
Main Authors: WANYIRI, Jane W, KANYI, Henry, MWAMBURI, Mkaya, WARD, Honorine D, MAINA, Samuel, WANG, David E, NGUGI, Paul, O'CONNOR, Roberta, KAMAU, Timothy, WAITHERA, Tabitha, KIMANI, Gachuhi, WAMAE, Claire N
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
CD4 Lymphocyte Count
Cross-Sectional Studies
Diarrhea - epidemiology
Diarrhea - etiology
Diarrhea - microbiology
Diarrhea - parasitology
Feces - microbiology
Feces - parasitology
Female
Gastroenterology. Liver. Pancreas. Abdomen
General aspects
HIV Infections - complications
HIV Infections - immunology
HIV Seropositivity - complications
Human viral diseases
Humans
Immunocompromised Host
Infectious diseases
Kenya - epidemiology
Male
Medical sciences
Middle Aged
Original
Other diseases. Semiology
Risk Factors
Sanitation - standards
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
Water Supply - standards
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Summary:Diarrhoea is a significant cause of morbidity and mortality in immunocompromised patients. The objectives of this study were to investigate the aetiological agents, risk factors and clinical features associated with diarrhoea in HIV/AIDS patients in Kenya. Sociodemographic, epidemiological and clinical data were obtained for 164 HIV/AIDS patients (70 with and 94 without diarrhoea) recruited from Kenyatta National Hospital, Kenya. Stool samples were examined for enteric pathogens by microscopy and bacteriology. Intestinal protozoa and fungi were identified in 70% of patients, more frequently in those with diarrhoea (p
ISSN:0035-9203
1878-3503
DOI:10.1093/trstmh/trt078