Exploiting pathogens' tricks of the trade for engineering of plant disease resistance: challenges and opportunities

Summary With expansion of our understanding of pathogen effector strategies and the multiplicity of their host targets, it is becoming evident that novel approaches to engineering broad‐spectrum resistance need to be deployed. The increasing availability of high temporal gene expression data of a ra...

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Bibliographic Details
Published in:Microbial biotechnology 2013-05, Vol.6 (3), p.212-222
Main Authors: Grant, Murray R., Kazan, Kemal, Manners, John M.
Format: Article
Language:English
Subjects:
Bacteria - genetics
Bacteria - pathogenicity
Crops, Agricultural - genetics
Disease Resistance - genetics
Genetic Engineering - methods
Minireviews
Plant Diseases - genetics
Plant Diseases - immunology
Plant Diseases - microbiology
Plant Proteins - genetics
Plant Proteins - metabolism
Plants, Genetically Modified - genetics
Plants, Genetically Modified - microbiology
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Summary:Summary With expansion of our understanding of pathogen effector strategies and the multiplicity of their host targets, it is becoming evident that novel approaches to engineering broad‐spectrum resistance need to be deployed. The increasing availability of high temporal gene expression data of a range of plant–microbe interactions enables the judicious choices of promoters to fine‐tune timing and magnitude of expression under specified stress conditions. We can therefore contemplate engineering a range of transgenic lines designed to interfere with pathogen virulence strategies that target plant hormone signalling or deploy specific disease resistance genes. An advantage of such an approach is that hormonal signalling is generic so if this strategy is effective, it can be easily implemented in a range of crop species. Additionally, multiple re‐wired lines can be crossed to develop more effective responses to pathogens.
ISSN:1751-7915
1751-7915
DOI:10.1111/1751-7915.12017