Project Impact: A pharmacotherapy pilot trial investigating the abstinence and treatment adherence of Latino light smokers

Abstract Light smoking is particularly prevalent among Latino smokers. Nicotine replacement (NRT) and varenicline are effective medications for smoking cessation for moderate-heavy smokers but have not been tested in light smokers, and thus, there are no treatment guidelines for use with light smoke...

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Bibliographic Details
Published in:Journal of substance abuse treatment 2012-10, Vol.43 (3), p.322-330
Main Authors: de Dios, Marcel A., Ph.D, Anderson, Bradley J., Ph.D, Stanton, Cassandra, Ph.D, Audet, Daniel A., B.A, Stein, Michael, M.D
Format: Article
Language:English
Subjects:
Abstinence
Adherence
Adult
Behavior Therapy
Benzazepines - therapeutic use
Combined Modality Therapy
Double-Blind Method
Drug therapy
Female
Follow-Up Studies
Hispanic Americans
Hispanic or Latino
Hispanics
Humans
Latin American people
Latinos
Light smokers
Male
Medication Adherence
Middle Aged
Nicotine replacement therapy
Nicotinic Agonists - therapeutic use
NRT
Pilot Projects
Psychiatry
Quinoxalines - therapeutic use
Recurrence
Smoking
Smoking cessation
Smoking Cessation - ethnology
Smoking Cessation - methods
Substance abuse treatment
Time Factors
Tobacco Use Cessation Devices
Tobacco Use Disorder - ethnology
Tobacco Use Disorder - rehabilitation
Transdermal medication
Treatment Outcome
Varenicline
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Summary:Abstract Light smoking is particularly prevalent among Latino smokers. Nicotine replacement (NRT) and varenicline are effective medications for smoking cessation for moderate-heavy smokers but have not been tested in light smokers, and thus, there are no treatment guidelines for use with light smokers. This pilot trial tested the efficacy of NRT and varenicline in increasing smoking abstinence among Latino light smokers. A 3-group (NRT, varenicline, and varenicline-placebo) randomized design was used, and Latino light smokers (≤10 cigarettes per day) received 12 weeks of treatment, which included a culturally informed behavioral health session and ongoing medication management visits. At follow-up, there were no abstinent participants in the placebo and NRT groups. However, 30% of participants in the varenicline group were abstinent at the 3-, 4-, and 6-month follow-up. This study represents the only investigation that specifically targets Latino light smokers using these treatments and characterizing their treatment adherence.
ISSN:0740-5472
1873-6483
DOI:10.1016/j.jsat.2012.01.004