Effects of obesity on lower urinary tract symptoms in Korean BPH patients

We analyzed the effects of obesity on lower urinary tract symptoms （LUTSs） in Korean benign prostatic hyperplasia （BPH） patients. This is a multicenter, cross-sectional, prospective study conducted in four centers in Korea. A total of 602 men with LUTSs secondary to BPH were included. BPH/LUTSs case...

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Bibliographic Details
Published in:Asian journal of andrology 2009-11, Vol.11 (6), p.663-668
Main Authors: Lee, Seung Hwan, Kim, Joon Chul, Lee, Ji-Youl, Kim, Jang Hwan, Oh, Cheol Young, Lee, Seung Wook, Yoo, Se Jeong, Chung, Byung Ha
Format: Article
Language:English
Subjects:
Adult
Asian Continental Ancestry Group
Cross-Sectional Studies
Humans
Korea
Male
Obesity - complications
Original
Prospective Studies
Prostate - pathology
Prostatic Hyperplasia - etiology
Prostatic Hyperplasia - pathology
Prostatic Hyperplasia - physiopathology
Waist Circumference
良性前列腺增生
质量指数
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Summary:We analyzed the effects of obesity on lower urinary tract symptoms （LUTSs） in Korean benign prostatic hyperplasia （BPH） patients. This is a multicenter, cross-sectional, prospective study conducted in four centers in Korea. A total of 602 men with LUTSs secondary to BPH were included. BPH/LUTSs cases were men aged ≥ 40 years with intemational prostate symptom scores （IPSS） ≥ 8 points. Height, weight and waist circumference were measured. Among the 602 patients, 156 patients had a waist circumference above 90 cm, representing central obesity, and 215 patients had a body mass index above 25 kg m2. Waist circumference was positively correlated with prostate volume （P = 0.034）. Men with waist circumference 〉 90 cm experienced a 1.36-fold increased risk of severe LUTSs （95% CI 0.82-2.41） compared with men with waist circumference ≤ 90 cm. Prostate volume was positively correlated with urgency and nocturia in men with central obesity. In this population of Korean men diagnosed with BPH, central obesity rather than overall obesity seems to be the more important predictor of LUTSs correlated with BPH.
ISSN:1008-682X
1745-7262
DOI:10.1038/aja.2009.62