Temporal Trends in the Prevalence of Diabetic Kidney Disease in the United States

CONTEXT Diabetes is the leading cause of kidney disease in the developed world. Over time, the prevalence of diabetic kidney disease (DKD) may increase due to the expanding size of the diabetes population or decrease due to the implementation of diabetes therapies. OBJECTIVE To define temporal chang...

Full description

Saved in:
Bibliographic Details
Published in:JAMA : the journal of the American Medical Association 2011-06, Vol.305 (24), p.2532-2539
Main Authors: de Boer, Ian H, Rue, Tessa C, Hall, Yoshio N, Heagerty, Patrick J, Weiss, Noel S, Himmelfarb, Jonathan
Format: Article
Language:English
Subjects:
Adult
Aged
Albuminuria
Biological and medical sciences
Cross-Sectional Studies
Diabetes
Diabetes Mellitus - epidemiology
Diabetes. Impaired glucose tolerance
Diabetic Nephropathies - epidemiology
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Epidemiology
Etiopathogenesis. Screening. Investigations. Target tissue resistance
Female
General aspects
Glomerular Filtration Rate
Humans
Hypoglycemic Agents - therapeutic use
Kidney diseases
Male
Medical sciences
Middle Aged
Nutrition Surveys
Prevalence
Public health
Public health. Hygiene
Public health. Hygiene-occupational medicine
Renin-Angiotensin System - drug effects
Time Factors
Trends
United States - epidemiology
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:CONTEXT Diabetes is the leading cause of kidney disease in the developed world. Over time, the prevalence of diabetic kidney disease (DKD) may increase due to the expanding size of the diabetes population or decrease due to the implementation of diabetes therapies. OBJECTIVE To define temporal changes in DKD prevalence in the United States. DESIGN, SETTING, AND PARTICIPANTS Cross-sectional analyses of the Third National Health and Nutrition Examination Survey (NHANES III) from 1988-1994 (N = 15 073), NHANES 1999-2004 (N = 13 045), and NHANES 2005-2008 (N = 9588). Participants with diabetes were defined by levels of hemoglobin A1c of 6.5% or greater, use of glucose-lowering medications, or both (n = 1431 in NHANES III; n = 1443 in NHANES 1999-2004; n = 1280 in NHANES 2005-2008). MAIN OUTCOME MEASURES Diabetic kidney disease was defined as diabetes with albuminuria (ratio of urine albumin to creatinine ≥30 mg/g), impaired glomerular filtration rate (
ISSN:0098-7484
1538-3598
DOI:10.1001/jama.2011.861