The effect of smoking on bone healing: A systematic review

To review the systemic impact of smoking on bone healing as evidenced within the orthopaedic literature. A protocol was established and studies were sourced from five electronic databases. Screening, data abstraction and quality assessment was conducted by two review authors. Prospective and retrosp...

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Bibliographic Details
Published in:Bone & joint research 2013-06, Vol.2 (6), p.102-111
Main Authors: Patel, R A, Wilson, R F, Patel, P A, Palmer, R M
Format: Article
Language:English
Subjects:
Bone Healing
Bone Repair
Fracture Healing
Smoking
Systematic Review
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Summary:To review the systemic impact of smoking on bone healing as evidenced within the orthopaedic literature. A protocol was established and studies were sourced from five electronic databases. Screening, data abstraction and quality assessment was conducted by two review authors. Prospective and retrospective clinical studies were included. The primary outcome measures were based on clinical and/or radiological indicators of bone healing. This review specifically focused on non-spinal orthopaedic studies. Nine tibia studies and eight other orthopaedic studies were considered for systematic review. Of these 17 studies, 13 concluded that smoking negatively influenced bone healing. Smoking has a negative effect on bone healing, in terms of delayed union, nonunion and more complications.
ISSN:2046-3758
2046-3758
DOI:10.1302/2046-3758.26.2000142