Urinary incontinence induced by tramadol

[4] These receptors are involved in both positive (5-HT4 and 5-HT7) and negative (5-HT1A) feedback mechanisms regulating cholinergic transmission; activation of excitatory serotonin receptors may cause reflex relaxation of the urethral sphincter along with detrusor contraction. [...]parasympathetic...

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Bibliographic Details
Published in:Indian journal of palliative care 2013-01, Vol.19 (1), p.76-77
Main Authors: Gautam, Sujeet, Das, Pravin, Agarwal, Anil
Format: Article
Language:English
Subjects:
Cancer
Care and treatment
Dosage and administration
Gynecology
Letters to Editor
Risk factors
Serotonin
Tramadol
Urinary incontinence
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Summary:[4] These receptors are involved in both positive (5-HT4 and 5-HT7) and negative (5-HT1A) feedback mechanisms regulating cholinergic transmission; activation of excitatory serotonin receptors may cause reflex relaxation of the urethral sphincter along with detrusor contraction. [...]parasympathetic hyperactivity with pelvic floor relaxation might have contributed to urinary incontinence in these cases.
ISSN:0973-1075
1998-3735
DOI:10.4103/0973-1075.110244