The correlation of SUVmax with pathological characteristics of primary tumor and the value of Tumor/ Lymph node SUVmax ratio for predicting metastasis to lymph nodes in resected NSCLC patients

We aimed to investigate the correlation of maximum standardized uptake value (SUVmax) with pathological characteristics of primary tumor and to determine a Tumor/ Lymph node (T/LN) SUVmax ratio predicting metastasis to lymph nodes in NSCLC patients. Eighty-one NSCLC patients who had PET/CT examinati...

Full description

Saved in:
Bibliographic Details
Published in:Journal of cardiothoracic surgery 2013-04, Vol.8 (1), p.63-63, Article 63
Main Authors: Koksal, Deniz, Demirag, Funda, Bayiz, Hulya, Ozmen, Ozlem, Tatci, Ebru, Berktas, Bahadir, Aydoğdu, Koray, Yekeler, Erdal
Format: Article
Language:English
Subjects:
Adult
Aged
Carcinoma, Non-Small-Cell Lung - diagnosis
Carcinoma, Non-Small-Cell Lung - pathology
Carcinoma, Non-Small-Cell Lung - surgery
Development and progression
Female
Glucose
Histology
Hospitals
Humans
Hypotheses
Inflammation
Inflammation - pathology
Lung cancer
Lung cancer, Non-small cell
Lung Neoplasms - diagnosis
Lung Neoplasms - pathology
Lung Neoplasms - surgery
Lymph Nodes - pathology
Lymphatic Metastasis
Lymphatic system
Male
Medical imaging
Metastasis
Middle Aged
Multimodal Imaging
Necrosis
PET imaging
Positron-Emission Tomography
Ratios
ROC Curve
Squamous cell carcinoma
Studies
Surgery
Thoracic surgery
Tomography
Tomography, X-Ray Computed
Tumors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We aimed to investigate the correlation of maximum standardized uptake value (SUVmax) with pathological characteristics of primary tumor and to determine a Tumor/ Lymph node (T/LN) SUVmax ratio predicting metastasis to lymph nodes in NSCLC patients. Eighty-one NSCLC patients who had PET/CT examination at initial staging and subsequently underwent surgical resection were retrospectively evaluated. There were 100 PET/CT positive mediastinal or hilar lymph node stations. Pathological characteristics of the tumor such as largest tumor diameter, tumor histology, differentiation, number of mitosis, degree of stromal inflammation, necrosis; etiology of PET/CT positive lymph node stations; SUVmax of primary tumor and positive lymph node stations were recorded. A T/LN SUVmax ratio was calculated for each lymph node station. SUVmax of the primary tumor was positively correlated with the largest tumor diameter (p=0.001, r=0.374), number of mitosis (p
ISSN:1749-8090
1749-8090
DOI:10.1186/1749-8090-8-63