Early evaluation predicts pain relief of irradiated bone metastases: a single-center prospective study

Radiation therapy is a well-recognized, effective modality used for palliative care. Most studies completed to date have endpoints of one month or greater after treatment completion. This study analyzed the response rates at different time points during the first month after treatment. From May 2010...

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Bibliographic Details
Published in:BMC palliative care 2013-03, Vol.12 (1), p.12-12, Article 12
Main Authors: Truntzer, Pierre, Atlani, David, Pop, Marius, Clavier, Jean-Baptiste, Guihard, Sébastien, Schumacher, Catherine, Noel, Georges
Format: Article
Language:English
Subjects:
Analgesics
Analysis
Bone
Bone cancer
Cancer
Cancer pain
Cancer therapies
Care and treatment
Life expectancy
Medical treatment
Metastasis
Pain
Palliative care
Palliative treatment
Radiation
Radiation therapy
Radiotherapy
Statistical analysis
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Summary:Radiation therapy is a well-recognized, effective modality used for palliative care. Most studies completed to date have endpoints of one month or greater after treatment completion. This study analyzed the response rates at different time points during the first month after treatment. From May 2010 to November 2011, 61 patients treated for 74 metastases were included in the study. The end points were defined as the completion of treatment (CT) and d8, d15 and d30 after the completion of treatment. The response rate was measured by the worst pain in the last 24 hours and the administered opioid dose. Patient assessment was performed during consultations and phone appointments. The overall response rate significantly improved from the CT (38%) to d8 (53.8%), d15 (53.8%) and d30 (57.1%) (respectively p 
ISSN:1472-684X
1472-684X
DOI:10.1186/1472-684X-12-12