Cryptic and asymptomatic Opisthorchis felineus infections

We describe the diagnostic difficulties experienced during an opisthorchiasis outbreak. Of 31 infected individuals, 61.3% were asymptomatic, and in the 12 symptomatic individuals, the duration of non-pathognomonic symptoms was shorter than 4 weeks. Serology by enzyme-linked immunosorbent assay and p...

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Bibliographic Details
Published in:The American journal of tropical medicine and hygiene 2013-02, Vol.88 (2), p.364-366
Main Authors: Armignacco, Orlando, Ferri, Fabrizio, Gomez-Morales, Maria Angeles, Caterini, Luciano, Pozio, Edoardo
Format: Article
Language:English
Subjects:
Adult
Aged
Albendazole - therapeutic use
Animals
Disease Outbreaks
DNA, Helminth - genetics
Dose-Response Relationship, Drug
Feces - chemistry
Feces - parasitology
Female
Humans
Immunoglobulin G - blood
Male
Mebendazole - therapeutic use
Middle Aged
Opisthorchiasis - diagnosis
Opisthorchiasis - drug therapy
Opisthorchis - drug effects
Opisthorchis - genetics
Opisthorchis - isolation & purification
Polymerase Chain Reaction
Praziquantel - therapeutic use
Short Report
Treatment Outcome
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Summary:We describe the diagnostic difficulties experienced during an opisthorchiasis outbreak. Of 31 infected individuals, 61.3% were asymptomatic, and in the 12 symptomatic individuals, the duration of non-pathognomonic symptoms was shorter than 4 weeks. Serology by enzyme-linked immunosorbent assay and polymerase chain reaction fecal analysis were shown to be the most sensitive diagnostic tools.
ISSN:0002-9637
1476-1645
DOI:10.4269/ajtmh.2012.12-0280