Usefulness of the Six-Minute Walk Test After Continuous Axial Flow Left Ventricular Device Implantation to Predict Survival

The goal of this study was to describe the predictors and significance of poor exercise tolerance after left ventricular assist device (LVAD) implantation. Despite LVAD therapy, some patients continue to exhibit exercise intolerance. The predictors and outcomes of these patients are unknown. A retro...

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Bibliographic Details
Published in:The American journal of cardiology 2012-11, Vol.110 (9), p.1322-1328
Main Authors: Hasin, Tal, MD, Topilsky, Yan, MD, Kremers, Walter K., PhD, Boilson, Barry A., MD, Schirger, John A., MD, Edwards, Brooks S., MD, Clavell, Alfredo L., MD, Rodeheffer, Richard J., MD, Frantz, Robert P., MD, Joyce, Lyle, MD, Daly, Richard, MD, Stulak, John M., MD, Kushwaha, Sudhir S., MD, Park, Soon J., MD, Pereira, Naveen L., MD
Format: Article
Language:English
Subjects:
Age Factors
Aged
Analysis of Variance
Biological and medical sciences
Cardiology. Vascular system
Cardiovascular
Clinical medicine
Cohort Studies
Exercise Test - methods
Exercise Tolerance - physiology
Female
Heart failure
Heart Failure - diagnosis
Heart Failure - mortality
Heart Failure - surgery
Heart rate
Heart-Assist Devices
Humans
Male
Medical sciences
Middle Aged
Monitoring, Physiologic - methods
Mortality
Multivariate Analysis
Odds Ratio
Postoperative Care - methods
Predictive Value of Tests
Prognosis
Proportional Hazards Models
Retrospective Studies
Risk Assessment
Sensitivity analysis
Sex Factors
Studies
Survival Analysis
Time Factors
Treatment Outcome
Variables
Ventilation
Walking - physiology
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Description
Summary:The goal of this study was to describe the predictors and significance of poor exercise tolerance after left ventricular assist device (LVAD) implantation. Despite LVAD therapy, some patients continue to exhibit exercise intolerance. The predictors and outcomes of these patients are unknown. A retrospective review of 65 LVAD recipients who performed 6-minute walk tests was conducted. Patients walking 50) univariate predictors identified diabetes mellitus (odds ratio 10.493, p = 0.003) and elevated 1-month right atrial pressure (odds ratio 2.985 for every 5 mm Hg, p = 0.003) as significant predictors of poor performance (
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2012.06.036