PI3K-PKB/Akt pathway

Protein kinase B (PKB, or Akt) plays a role in cell metabolism, growth, proliferation, and survival. Its activation is controlled by a multi-step process that involves phosphoinositide-3-kinase (PI3K).

Saved in:
Bibliographic Details
Published in:Cold Spring Harbor perspectives in biology 2012-09, Vol.4 (9), p.a011189-a011189
Main Authors: Hemmings, Brian A, Restuccia, David F
Format: Article
Language:English
Subjects:
Models, Biological
Phosphatidylinositol 3-Kinases - metabolism
Phosphorylation
Primer
Proto-Oncogene Proteins c-akt - metabolism
Receptor Protein-Tyrosine Kinases - metabolism
Receptor Protein-Tyrosine Kinases - physiology
Signal Transduction
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Protein kinase B (PKB, or Akt) plays a role in cell metabolism, growth, proliferation, and survival. Its activation is controlled by a multi-step process that involves phosphoinositide-3-kinase (PI3K).
ISSN:1943-0264
1943-0264
DOI:10.1101/cshperspect.a011189