Long-Term Cardiovascular Outcomes in Patients With Angina Pectoris Presenting With Bundle Branch Block

Long-term outcomes of unselected patients with angina pectoris and bundle branch block (BBB) on initial electrocardiogram are not well established. The Olmsted County Chest Pain Study is a community-based cohort of 2,271 consecutive patients presenting to 3 Olmsted County emergency departments with...

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Bibliographic Details
Published in:The American journal of cardiology 2011-06, Vol.107 (11), p.1565-1570
Main Authors: Bansilal, Sameer, MD, Aneja, Ashish, MD, Mathew, Verghese, MD, Reeder, Guy S., MD, Smars, Peter A., MD, Lennon, Ryan J., MS, Wiste, Heather J., BA, Traverse, Kay, RN, Farkouh, Michael E., MD
Format: Article
Language:English
Subjects:
Angina pectoris
Angina Pectoris - complications
Angina Pectoris - diagnosis
Biological and medical sciences
Bundle-Branch Block - complications
Bundle-Branch Block - diagnosis
Cardiac dysrhythmias
Cardiology
Cardiology. Vascular system
Cardiovascular
Coronary heart disease
Electrocardiography
Female
Heart
Humans
Male
Medical sciences
Middle Aged
Mortality
Prognosis
Risk factors
Time Factors
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Summary:Long-term outcomes of unselected patients with angina pectoris and bundle branch block (BBB) on initial electrocardiogram are not well established. The Olmsted County Chest Pain Study is a community-based cohort of 2,271 consecutive patients presenting to 3 Olmsted County emergency departments with angina from 1985 through 1992. Patients were followed for major adverse cardiovascular events (MACEs) including death, myocardial infarction, stroke, and revascularization at 30 days and over a median follow-up period of 7.3 years and for mortality only through a median of 16.6 years. Cox models were used to estimate associations between BBB and cardiovascular outcomes. Mean age of the cohort on presentation was 63 years, and 58% were men. MACEs at 30 days occurred in 11% with right BBB (RBBB), 8.8% with left BBB (LBBB), and 6.4% in patients without BBB (p = 0.17). Over a median follow-up of 7.3 years, patients with BBB were at higher risk for MACEs (RBBB, hazard ratio [HR] 1.85, 95% confidence interval [CI] 1.44 to 2.38, p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2011.01.039