TNFα Is Required for Late BRB Breakdown in Diabetic Retinopathy, and Its Inhibition Prevents Leukostasis and Protects Vessels and Neurons from Apoptosis

The absence of TNFα protects against diabetes-associated blood–retinal barrier breakdown, leukostasis, and apoptosis in the retina, making it a good therapeutic target for the prevention of the progressive BRB breakdown, inflammation, and apoptosis associated with diabetic retinopathy.

Bibliographic Details

Published in:	Investigative ophthalmology & visual science 2011-03, Vol.52 (3), p.1336-1344
Main Authors:	Huang, Hu, Gandhi, Jarel K., Zhong, Xiufeng, Wei, Yanhong, Gong, Junsong, Duh, Elia J., Vinores, Stanley A.
Format:	Article
Language:	English
Citations:	Items that cite this one
Online Access:	Get full text
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