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Influence of individual saliva secretion on fluoride bioavailability

The aim of this preliminary investigation was to compare the individual saliva secretion rate with the fluoride bioavailability in saliva after using sodium fluoride and amine fluoride. To assess oral fluoride kinetics 10 highly trained volunteers brushed their teeth with one of the formulations and...

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Bibliographic Details
Published in:The open dentistry journal 2010-08, Vol.4 (1), p.185-190
Main Authors: Naumova, E A, Gaengler, P, Zimmer, S, Arnold, W H
Format: Article
Language:English
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Summary:The aim of this preliminary investigation was to compare the individual saliva secretion rate with the fluoride bioavailability in saliva after using sodium fluoride and amine fluoride. To assess oral fluoride kinetics 10 highly trained volunteers brushed their teeth with one of the formulations and saliva was collected. The amount of saliva was measured, and the fluoride content was determined. Data underwent statistical analysis using the Mann-Whitney-U test and Pearson correlation. The ex vivo experiment I included individual saliva collection of the same volunteers. Then the oral hygiene products were solved in equal amounts of whole saliva (ex-vivo experiment II), and the fluoride content was measured. Finally, both products were dispersed in distilled water (ex-vivo experiment III) to calculate the dissociation of both products in water. In vivo results of fluoride content after 3 min. tooth brushing demonstrated a negative correlation with saliva secretion: for NaF r = -0.695 (p
ISSN:1874-2106
1874-2106
DOI:10.2174/1874210601004010185