Sleep Duration and the Risk of Diabetes Mellitus: Epidemiologic Evidence and Pathophysiologic Insights

Evidence from well-defined cohort studies has shown that short sleep, through sleep fragmentation caused by obstructive sleep apnea (OSA) or behavioral sleep curtailment because of lifestyle choices, is associated with increased incidence of diabetes. In this report, we review epidemiologic and clin...

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Bibliographic Details
Published in:Current diabetes reports 2010-02, Vol.10 (1), p.43-47
Main Authors: Zizi, Ferdinand, Jean-Louis, Girardin, Brown, Clinton D., Ogedegbe, Gbenga, Boutin-Foster, Carla, McFarlane, Samy I.
Format: Article
Language:English
Subjects:
Diabetes
Diabetes Mellitus - epidemiology
Diabetes Mellitus - physiopathology
Humans
Medicine
Medicine & Public Health
Risk Factors
Sleep - physiology
Sleep Apnea, Obstructive - complications
Sleep Apnea, Obstructive - physiopathology
Sleep Apnea, Obstructive - therapy
Sleep Deprivation - complications
Sleep Deprivation - physiopathology
Time Factors
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Summary:Evidence from well-defined cohort studies has shown that short sleep, through sleep fragmentation caused by obstructive sleep apnea (OSA) or behavioral sleep curtailment because of lifestyle choices, is associated with increased incidence of diabetes. In this report, we review epidemiologic and clinical data suggesting that OSA is involved in the pathogenesis of altered glucose metabolism. Evidence suggesting increased risk of developing diabetes resulting from curtailed sleep duration is also considered. Proposed mechanisms explaining associations between short sleep and diabetes are examined and clinical management of OSA among patients with diabetes is discussed.
ISSN:1534-4827
1539-0829
DOI:10.1007/s11892-009-0082-x