Ultrasonic backscatter coefficients for weakly scattering, agar spheres in agar phantoms

Applicability of ultrasound phantoms to biological tissue has been limited because most phantoms have generally used strong scatterers. The objective was to develop very weakly scattering phantoms, whose acoustic scattering properties are likely closer to those of tissues and then compare theoretica...

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Bibliographic Details
Published in:The Journal of the Acoustical Society of America 2010-08, Vol.128 (2), p.903-908
Main Authors: King, Michael R., Anderson, Janelle J., Herd, Maria-Teresa, Ma, Darryl, Haak, Alexander, Wirtzfeld, Lauren A., Madsen, Ernest L., Zagzebski, James A., Oelze, Michael L., Hall, Timothy J., O'Brien, William D.
Format: Article
Language:English
Subjects:
Agar
Animals
Bioacoustics
Biological and medical sciences
Investigative techniques, diagnostic techniques (general aspects)
Medical sciences
Microspheres
Milk
Miscellaneous. Technology
Models, Theoretical
Observer Variation
Particle Size
Phantoms, Imaging
Reproducibility of Results
Scattering, Radiation
Ultrafiltration
Ultrasonic investigative techniques
Ultrasonography - instrumentation
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Summary:Applicability of ultrasound phantoms to biological tissue has been limited because most phantoms have generally used strong scatterers. The objective was to develop very weakly scattering phantoms, whose acoustic scattering properties are likely closer to those of tissues and then compare theoretical simulations and experimental backscatter coefficient (BSC) results. The phantoms consisted of agar spheres of various diameters (nominally between 90 and 212   μ m ), containing ultrafiltered milk, suspended in an agar background. BSC estimates were performed at two institutions over the frequency range 1-13 MHz, and compared to three models. Excellent agreement was shown between the two laboratory results as well as with the three models.
ISSN:0001-4966
1520-8524
DOI:10.1121/1.3460109