The pathophysiological mechanism underlying Brugada syndrome: Depolarization versus repolarization

This Point/Counterpoint presents a scholarly debate of the mechanisms underlying the electrocardiographic and arrhythmic manifestations of Brugada syndrome (BrS), exploring in detail the available evidence in support of the repolarization vs. depolarization hypothesis.

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Bibliographic Details
Published in:Journal of molecular and cellular cardiology 2010-10, Vol.49 (4), p.543-553
Main Authors: Wilde, Arthur A.M., Postema, Pieter G., Di Diego, José M., Viskin, Sami, Morita, Hiroshi, Fish, Jeffrey M., Antzelevitch, Charles
Format: Article
Language:English
Subjects:
Animals
Arrhythmias, Cardiac - physiopathology
Brugada syndrome
Brugada Syndrome - physiopathology
Cardiac Electrophysiology - methods
Depolarization versus repolarization
Electrocardiography
Humans
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Description
Summary:This Point/Counterpoint presents a scholarly debate of the mechanisms underlying the electrocardiographic and arrhythmic manifestations of Brugada syndrome (BrS), exploring in detail the available evidence in support of the repolarization vs. depolarization hypothesis.
ISSN:0022-2828
1095-8584
DOI:10.1016/j.yjmcc.2010.07.012