When Children With Kawasaki Disease Grow Up: Myocardial and Vascular Complications in Adulthood

Kawasaki disease (KD) is an acute, self-limited vasculitis that typically occurs in young children and was first described by Japanese pediatrician Tomisaku Kawasaki in 1967. Although originally thought to be a rare condition, KD has become the most common cause of acquired heart disease in the pedi...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2009-11, Vol.54 (21), p.1911-1920
Main Authors: GORDON, John B, KAHN, Andrew M, BURNS, JaneC
Format: Article
Language:English
Subjects:
Adult
Aspirin
Atherosclerosis
Biological and medical sciences
Cardiology
Cardiology. Vascular system
Cardiovascular disease
Child
Confidence intervals
Coronary Artery Disease - epidemiology
Coronary Artery Disease - etiology
Coronary vessels
Counseling
Disease Progression
Drug therapy
Heart attacks
Heart failure
Humans
Illnesses
Incidence
Ischemia
Medical imaging
Medical sciences
Mortality
Mucocutaneous Lymph Node Syndrome - complications
Myocardial Ischemia - epidemiology
Myocardial Ischemia - etiology
Risk assessment
Risk Factors
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Ultrasonic imaging
Young adults
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Summary:Kawasaki disease (KD) is an acute, self-limited vasculitis that typically occurs in young children and was first described by Japanese pediatrician Tomisaku Kawasaki in 1967. Although originally thought to be a rare condition, KD has become the most common cause of acquired heart disease in the pediatric age group in developed countries. The majority of patients with KD appear to have a benign prognosis, but a subset of patients with coronary artery aneurysms are at risk for ischemic events and require lifelong treatment. In the 4 decades that have passed since the initial recognition of KD, the number of patients reaching adulthood has continued to grow. Adult cardiologists will be increasingly involved in the management of these patients. Currently, there are no established guidelines for the evaluation and treatment of adult patients who have had KD. We review here the current literature that may be helpful to clinicians who care for adults who experienced KD in childhood.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2009.04.102