Sudden elevation of liver enzymes in a 64-year-old patient: a case report

Eradication of Helicobacter pylori usually consists of a 7-day course of triple therapy including metronidazole or amoxicillin plus clarithromycin plus a proton pump inhibitor. We report about a rare adverse event of Hp eradication in a patient with moderate chronic and moderate active pangastritis....

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Bibliographic Details
Published in:Cases journal 2009-11, Vol.2 (1), p.205-205, Article 205
Main Authors: Wiedmann, Marcus, Müller, Constanze, Lobeck, Hartmut, Wölke, Katharina
Format: Article
Language:English
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Case Report
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Summary:Eradication of Helicobacter pylori usually consists of a 7-day course of triple therapy including metronidazole or amoxicillin plus clarithromycin plus a proton pump inhibitor. We report about a rare adverse event of Hp eradication in a patient with moderate chronic and moderate active pangastritis. Shortly after the end of treatment cholestatic hepatitis occurred which was most likely related to clarithromycin, perhaps enhanced by amoxicillin. Since liver dysfunction was self-limited, no further treatment was required. In summary, clinicians should be aware about the presented rare adverse event of Helicobacter pylori eradication treatment for a close monitoring of those patients and rapid management of acute liver failure.
ISSN:1757-1626
1757-1626
DOI:10.1186/1757-1626-2-205