Natural products and drug discovery. Can thousands of years of ancient medical knowledge lead us to new and powerful drug combinations in the fight against cancer and dementia?

Natural products have often been the sole means to treat diseases and injuries. in fact, it has only been during the past decades that natural products have taken a secondary role in drug discovery and drug development, after the advent of molecular biology and combinatorial chemistry made possible...

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Bibliographic Details
Published in:EMBO reports 2009-03, Vol.10 (3), p.194-200
Main Authors: Ji, Hong-Fang, Li, Xue-Juan, Zhang, Hong-Yu
Format: Article
Language:English
Subjects:
Animals
Biochemistry
Biological Products - therapeutic use
Dementia - drug therapy
Drug Discovery
Herbal medicine
History of Medicine
Humans
Medicine, Traditional
Molecular biology
Molecular Conformation
Natural products
Neoplasms - drug therapy
Pharmacology
Plant Extracts - chemistry
Plant Extracts - therapeutic use
Science and Society
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Summary:Natural products have often been the sole means to treat diseases and injuries. in fact, it has only been during the past decades that natural products have taken a secondary role in drug discovery and drug development, after the advent of molecular biology and combinatorial chemistry made possible the rational design of chemical compounds to target specific molecules. The past few years, however, have seen a renewed interest in the use of natural compounds and, more importantly, their role as a basis for drug development.
ISSN:1469-221X
1469-3178
DOI:10.1038/embor.2009.12