Antimicrobial use on 24 beef farms in Ontario

Understanding risk factors for antimicrobial resistance requires knowledge of antimicrobial selection pressure. The objectives of this research were to develop methodology for collecting quantitative antimicrobial use information from beef producers in Ontario, to document the types and quantities o...

Full description

Saved in:
Bibliographic Details
Published in:Canadian journal of veterinary research 2008-01, Vol.72 (2), p.109-118
Main Authors: Carson, C.A, Reid-Smith, R, Irwin, R.J, Martin, W.S, McEwen, S.A
Format: Article
Language:English
Subjects:
Age Factors
Animals
Animals, Newborn
Anti-Bacterial Agents - administration & dosage
Anti-Bacterial Agents - pharmacology
Anti-Bacterial Agents - supply & distribution
antibiotic resistance
antimicrobial agents
beef cattle
Cattle
Cattle Diseases - drug therapy
Cattle Diseases - epidemiology
Cattle Diseases - microbiology
Colony Count, Microbial - veterinary
Dose-Response Relationship, Drug
Drug Resistance, Bacterial
Drug Resistance, Multiple, Bacterial
Drug Utilization - statistics & numerical data
Escherichia coli - drug effects
Escherichia coli - isolation & purification
Escherichia coli Infections - drug therapy
Escherichia coli Infections - epidemiology
Escherichia coli Infections - microbiology
Escherichia coli Infections - veterinary
farm surveys
Feces - microbiology
Female
Injections - veterinary
Male
Microbial Sensitivity Tests - veterinary
Ontario
Prevalence
Risk Factors
Seasons
Sex Factors
Surveys and Questionnaires
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Understanding risk factors for antimicrobial resistance requires knowledge of antimicrobial selection pressure. The objectives of this research were to develop methodology for collecting quantitative antimicrobial use information from beef producers in Ontario, to document the types and quantities of antimicrobials reported (for a minimum of 12 mo), and to compare 2 metrics for injectable use reporting. Twenty-four volunteer beef producers were asked to complete a questionnaire, document drug use in a treatment diary, and retain empty medication containers. For injectable antimicrobials, producers recorded approximately 60% of the total use in the treatment diaries; oxytetracycline, penicillin, macrolides, florfenicol, and spectinomycin were used in the greatest quantities. Based on estimated weights of active ingredients (calculated according to number of animals exposed, duration, and average dose per day) the antimicrobials most commonly used in feed were monensin, tylosin, lasalocid, and tetracyclines. The antimicrobials most commonly used in water were lincomycin-spectinomycin, chlortetracycline, and oxytetracycline. Based on estimated weights and measured quantities, < 1% of antimicrobials used were in the Canadian category of highest importance to human medicine. A comparison of animal daily dosages to kilograms of active ingredient demonstrated that the relative ranking of use of antimicrobials varied with the chosen metric, and that further investigation into the best measure in relation to antimicrobial resistance is warranted.
ISSN:0830-9000