Conconavalin A-stimulated bovine T-cell supernatants inhibit growth of Cowdria ruminantium in bovine endothelial cells in vitro

Conconavalin A-stimulated bovine T-cell supernatants inhibited the growth of Cowdria ruminantium in bovine endothelial cells in vitro but did not affect their entry. This finding represents one mechanism by which T cells may control C. ruminantium multiplication and hence affect the severity of dise...

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Bibliographic Details
Published in:Infection and Immunity 1994-02, Vol.62 (2), p.747-750
Main Authors: MAHAN, S. M, SMITH, G. E, BYROM, B
Format: Article
Language:English
Subjects:
Analysis of the immune response. Humoral and cellular immunity
Animals
Biological and medical sciences
bovin
Cattle
Cell interactions
Cell Line
citoquininas
Concanavalin A - pharmacology
cowdria
Cowdria ruminantium
Cytokines - pharmacology
cytokinine
cytokinins
Ehrlichia ruminantium - growth & development
Ehrlichia ruminantium - immunology
Endothelium, Vascular - immunology
Endothelium, Vascular - microbiology
experimentacion in vitro
experimentation in vitro
Fundamental and applied biological sciences. Psychology
Fundamental immunology
ganado bovino
Heartwater Disease - etiology
Heartwater Disease - immunology
Immunobiology
in vitro experimentation
In Vitro Techniques
Interferon-gamma - pharmacology
T-Lymphocytes - immunology
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Description
Summary:Conconavalin A-stimulated bovine T-cell supernatants inhibited the growth of Cowdria ruminantium in bovine endothelial cells in vitro but did not affect their entry. This finding represents one mechanism by which T cells may control C. ruminantium multiplication and hence affect the severity of disease.
ISSN:0019-9567
1098-5522
DOI:10.1128/IAI.62.2.747-750.1994