Leukotriene receptor antagonists as potential steroid sparing agents in a patient with serosal eosinophilic gastroenteritis

Serosal involvement causes exudative ascites rich in eosinophils; this is the least common form and is usually diagnosed by laparoscopic examination and biopsy of the whole intestinal wall. 1, 2 We present the case of an 18 year old male student with a history of allergic rhinitis presenting with ab...

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Bibliographic Details
Published in:Gut 2006-09, Vol.55 (9), p.1363-1364
Main Authors: Urek, M C, Kujundžić, M, Banić, M, Urek, R, Veić, T Š, Kardum, D
Format: Article
Language:English
Subjects:
Abdomen
Acetates - therapeutic use
Adolescent
Allergies
Biopsy
Endoscopy
Eosinophilia - drug therapy
gastroenteritis
Gastroenteritis - drug therapy
Glucocorticoids - therapeutic use
Humans
Inflammation
Laboratories
Letters
Leukotriene Antagonists - therapeutic use
leukotriene receptor antagonists
leukotrienes
Male
Prednisolone - therapeutic use
Quinolines - therapeutic use
Recurrence
serosal eosinophilic gastroenteritis
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Summary:Serosal involvement causes exudative ascites rich in eosinophils; this is the least common form and is usually diagnosed by laparoscopic examination and biopsy of the whole intestinal wall. 1, 2 We present the case of an 18 year old male student with a history of allergic rhinitis presenting with abdominal pain, nausea, and low grade fever, which started a few weeks before his admission. Laboratory findings showed leucocytosis with a high percentage of eosinophils (81%); skin prick testing showed sensitivity to Dermatophagoides pteronyssinus and ragweed pollen; total immunoglobulin E in serum was three times the normal level (311 kI/l); and a bone marrow aspiration specimen showed increased numbers of mostly mature eosinophils (62%) in the differential cell count.
ISSN:0017-5749
1468-3288
DOI:10.1136/gut.2006.099465