Gastric duplication in an adult mimicking mucinous cystadenoma of the pancreas

Gastric duplication cyst (GDC) in an adult can have several clinical presentations. A review of the literature showed previously reported cases of GDC presenting as pancreatic pseudocyst or with greatly raised concentrations of carbohydrate antigen 19-9 (CA 19-9). It is often difficult to discrimina...

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Bibliographic Details
Published in:Journal of clinical pathology 2004-11, Vol.57 (11), p.1215-1218
Main Authors: D’Journo, X B, Moutardier, V, Turrini, O, Guiramand, J, Lelong, B, Pesenti, C, Monges, G, Giovannini, M, Delpero, J R
Format: Article
Language:English
Subjects:
adenocarcinoma
Adult
Adults
Antigens
Biological and medical sciences
carbohydrate antigen
Carbohydrates
carcinoembryonic antigen
Case Reports
CEA
computed tomography
Cystadenoma, Mucinous - diagnosis
Cysts
Cysts - congenital
Cysts - diagnosis
Cysts - pathology
cytokeratin
Diagnosis, Differential
endoscopic ultrasonography
Epithelium - pathology
EUS
Female
gastric duplication
gastric duplication cyst
gastrointestinal duplication
GDC
Humans
Investigative techniques, diagnostic techniques (general aspects)
Medical imaging
Medical sciences
Morphology
mucinous
Pancreas
Pancreatic Neoplasms - diagnosis
Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques
Smooth muscle
Spinal cord
Stomach
Stomach - abnormalities
Stomach Diseases - congenital
Stomach Diseases - diagnosis
Stomach Diseases - pathology
Surgery
Tomography, X-Ray Computed
Tumors
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Items that cite this one
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Description
Summary:Gastric duplication cyst (GDC) in an adult can have several clinical presentations. A review of the literature showed previously reported cases of GDC presenting as pancreatic pseudocyst or with greatly raised concentrations of carbohydrate antigen 19-9 (CA 19-9). It is often difficult to discriminate GDC from pancreatic cystic tumour, in particular pancreatic mucinous cystadenoma, in which concentrations of carcinoembryonic antigen and CA 19-9 are classically raised. This report describes an adult case of GDC mimicking a mucinous cystadenoma of the pancreas. This is the first report of a simultaneous increase in carcinoembryonic antigen and CA 19-9 in GDC in the absence of malignancy. Although few cases of carcinoma arising from a GDC having been reported, the production of oncofetal antigens raises the problem of a precancerous condition in long standing intestinal duplications. In this situation surgical resection must be performed.
ISSN:0021-9746
1472-4146
DOI:10.1136/jcp.2004.019091