Closure of patent foramen ovale: is the case really closed as well?

Assessment is further complicated by an index event, paradoxical embolism, which is almost never directly observed and usually only inferred. [...]neither whether the event is embolic nor whether other embolic sources are "ruled out" constitute iron-clad facts in clinical practice. In this...

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Bibliographic Details
Published in:Heart (British Cardiac Society) 2005-04, Vol.91 (4), p.449-450
Main Authors: Flachskampf, F A, Daniel, W G
Format: Article
Language:English
Subjects:
Aneurysms
Blood clots
Cardiac arrhythmia
Disease prevention
Embolism, Paradoxical - etiology
Embolisms
Health risk assessment
Heart attacks
Heart Septal Defects, Atrial - complications
Heart Septal Defects, Atrial - therapy
Humans
Mini-Symposium
patent foramen ovale
Patient Selection
Risk Factors
Thromboembolism
Thrombosis
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Summary:Assessment is further complicated by an index event, paradoxical embolism, which is almost never directly observed and usually only inferred. [...]neither whether the event is embolic nor whether other embolic sources are "ruled out" constitute iron-clad facts in clinical practice. In this mini-symposium, Amarenco reports that his group did not find an increased frequency of thrombophilia in patients with presumed paradoxical embolism, nor could they document an increased incidence of Valsalva manoeuvres (p 441 ). [...]local formation of thrombus in an atrial septal aneurysm or in the PFO itself is suggested as an alternative pathomechanism to venous thromboembolism.
ISSN:1355-6037
1468-201X
DOI:10.1136/hrt.2004.052217