Effect of body size on operative risk of carotid endarterectomy

Many studies have found that women have a higher risk of perioperative stroke or death from carotid endarterectomy. Other vascular surgical procedures have demonstrated that body size and morphology impact on operative risk. We correlated the 30 day operative risk of stroke and death in the European...

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Bibliographic Details
Published in:Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 2004-12, Vol.75 (12), p.1759-1761
Main Authors: Messé, S R, Kasner, S E, Mehta, Z, Warlow, C P, Rothwell, P M
Format: Article
Language:English
Subjects:
Age
Aged
Biological and medical sciences
BMI
Body Height
Body mass index
Body Surface Area
BSA
carotid arteries
carotid endarterectomy
CEA
Confidence intervals
Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
ECST
Endarterectomy, Carotid - adverse effects
Endarterectomy, Carotid - mortality
European Carotid Surgery Trial
Female
Humans
Male
Medical sciences
Middle Aged
Mortality
Neurology
Neurosurgery
Patients
Postoperative Complications
Postoperative period
Retrospective Studies
Risk Factors
Sex Factors
Sexes
Short Report
Skull, brain, vascular surgery
Stroke
Stroke - etiology
Studies
Surgery
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Variables
Women
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Summary:Many studies have found that women have a higher risk of perioperative stroke or death from carotid endarterectomy. Other vascular surgical procedures have demonstrated that body size and morphology impact on operative risk. We correlated the 30 day operative risk of stroke and death in the European Carotid Surgery Trial (ECST) with height, weight, body surface area (BSA), and body mass index using single variable analyses and multivariable logistic regression. Women were at significantly higher risk of perioperative stroke and death in the ECST. Both height and BSA confounded the effect of sex, implying that the generally smaller size of women may contribute to their increased risk. This finding should be validated in other large datasets.
ISSN:0022-3050
1468-330X
DOI:10.1136/jnnp.2003.030486